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tidymodules
An Object-Oriented approach to Shiny modulesYADA
Open-source Data Opspeax
Peax is a tool for interactive visual pattern search and exploration in epigenomic data based on unsupervised representation learning with autoencoderstorchsurv
Deep survival analysis made easyscar
scAR (single-cell Ambient Remover) is a deep learning model for removal of the ambient signals in droplet-based single cell omicscellxgene-gateway
Cellxgene Gateway allows you to use the Cellxgene Server provided by the Chan Zuckerberg Institute (https://github.com/chanzuckerberg/cellxgene) with multiple datasets.ontobrowser
OntoBrowser is a web-based application for managing ontologiesshinyValidator
Audit your Shiny apps at each commit. Multiple levels of testings are offered: startup and crash tests, performance tests (load test and global code profiling), reactivity audit as well as output tests. All results are gathered in an HTML report uploaded and available to everyone on any CI/CD plaform or RStudio Connectyap
High throughput, pain-free big data pipelines.pQSAR
Massively multitask stacked model for predicting activity of thousands of biological assaysChemBioMultimodalAutoencoders
a package for streamlined multidomain data integration and translation based on cross-modal autoencoders architecturespqsar2cpd
pqsar2cpd is a deep learning algorithm for translation of activity profiles into novel molecules.easyTrackHubs
This package provides a function to reformat lists of genome coverage files, such as bigWig of bam files, into the directory structure of a UCSC Track Hub ready to be visualized in the genome browser. For details about it's use, please have a look at the vignette of the package.pisces
PISCES is a pipeline for rapid transcript quantitation, genetic fingerprinting, and quality control assessment of RNAseq libraries using Salmon.JAEGER
JAEGER is a deep generative approach for small-molecule designCausal-inference-in-RCTs
This repository contains code examples for several methods in a Causal Inference in RCTs short course.patprofile
Standard patient profile for shiny appsDRUG-seq
DRUG (Digital RNA with pertUrbation of Genes)-seq data analysis pipelineMoaBox
A repository of compound-target annotations in support of Systematic Chemogenetic Library Assemblyrailroadtracks
Railroadtracks is a Python package to handle connected computation steps for DNA and RNA Seq.gridvar
GridVar is a jQuery plugin that visualizes multi-dimensional datasets as layers organized in a row-column format.xgxr
R package for supporting exploratory graphics at http://opensource.nibr.com/xgxJenkins-LSCI
Jenkins for Life Science Continuous Integrationgranulator
EQP-cluster
Unix-based RNA-seq quantification pipelinemdx-utils
AEGIS
MHC-II presentation predictorhpath
An ontology of histopathological morphologieshabitat
"Where files live" - Simple object management system using AWS S3 and Elasticsearch Service to manage objects and their metadataRBesT
Tool-set to support Bayesian evidence synthesis in RscRNAseq_workflow_benchmark
Workflow for the analysis fo single-cell RNASeq data using R/bioconductordiv_rank
This code allows is for diversity picking across multiple different, and potentially overlapping chemical compound classes, while at the same time optimizing a property score. This algorithm has been used in the re-design of the Novartis screening deck as described in https://dx.doi.org/10.1021/acs.jmedchem.0c01332subpat
{subpat} is a collection of modules to create subpopulations and subgroups from clinical trial dataAdvanced-User-Interfaces-for-Shiny-Developers
UMM-Discovery
UMM-Discovery is a fully unsupervised deep learning method to cluster cellular images with similar phenotypes together, solely based on the intensity values.toolscore
Script and example data for "Evidence-Based and Quantitative Prioritization of Tool Compounds in Phenotypic Drug Discovery"UNIQUE
A Python library for benchmarking uncertainty estimation and quantification methods for Machine Learning models predictionsMOBER
Multi-omics batch effect remover methodhdf5r
CellSIUS
CellSIUS: Cell Subtype Identification from Upregulated gene Setsdms-pipeline
Snakemake pipeline for quantification of deep mutational scanning (DMS) data from overlapping paired-end reads in fastq files from amplicon sequencingNDSRIs_in_silico_tool
N-nitrosamine Autonomous Carcinogenic Potency Categorization Approach Calculation Toolchraw
The package analyzes chromatin and multi-omic experiments. It extends the MultiAssayExperiment object and builds a ChrawExperiment object from ENCODEβs output. It performs QC plotting, identifies differential events and other functionalities. More details in package vignettes.Project-Mona-Lisa
Project Mona Lisa (PML): Machine-learning Assisted Diagramming PlatformpeakCombiner
The fully R based tool peakCombiner is a user-friendly, transparent, modular and customizable package with the purpose to create a consensus peak file from genomic input regions. The aim is to allow even novice R users to create good quality combined peak sets to be used as the starting point for most downstream differential analyses.verifyr
A package to hold R functions for comparing different version of clinical trial TLFsTRAWLING
Description: Build TRAWLING: a Transcriptome Reference AWare of spLicING eventsTAT
Transcriptomics-to-Activity Transformer (TAT) is a deep learning model to predict compound bioactivity in a dose-response assay using compound-induced transcriptomic profiles over concentration.nxc-chess
watMD
Water tool for molecular dynamics that calculates solvation fields for interaction between water and non-solvant moleculessolid-tumor-CHIP
Clonal hematopoiesis detection in cancer patients using cell free DNA sequencingNovartis.github.io
Public gallery of NIBR Open Source projectssidtoolbox
Subgroup identification toolboxProfile-QSAR
Massively multitask stacked model for predicting activity of thousands of biological assaysCu-Catalyzed-Ligands-Design
By establishing machine learning (ML) models, the design of ligands and optimization of reaction conditions were effectively facilitatedEQP-QM
Unix based RNA-seq quantification moduleGreyChemicalMatter
A pipeline to identify bioactive small molecules with likely novel modes of actions and dynamic SAR from historic cell-HTS profiles, with an example application and hitlist from PubChem datamvAC50
AC50 potencies from multivariate assay readouts like gene signatureschess-redux
mueller_et_al_2018
Processed data relating to Continuous monitoring of patient mobility for 18 months using inertial sensors following traumatic knee injury: a case study Mueller A., Hoefling H., Nuritdinow T., et al. Paper: http://doi.org/10.1159/000490919 Raw data: http://doi.org/10.5281/zenodo.1443190Love Open Source and this site? Check out how you can help us