>>> import mojimoji
>>> print mojimoji.zen_to_han(u'アイウａｂｃ０１２')
ｱｲｳabc012
>>> print mojimoji.zen_to_han(u'アイウａｂｃ０１２', kana=False)
アイウabc012
>>> print mojimoji.zen_to_han(u'アイウａｂｃ０１２', digit=False)
ｱｲｳabc０１２
>>> print mojimoji.zen_to_han(u'アイウａｂｃ０１２', ascii=False)
ｱｲｳａｂｃ012

>>> import mojimoji
>>> print mojimoji.han_to_zen(u'ｱｲｳabc012')
アイウａｂｃ０１２
>>> print mojimoji.han_to_zen(u'ｱｲｳabc012', kana=False)
ｱｲｳａｂｃ０１２
>>> print mojimoji.han_to_zen(u'ｱｲｳabc012', digit=False)
アイウａｂｃ012
>>> print mojimoji.han_to_zen(u'ｱｲｳabc012', ascii=False)
アイウabc０１２

In [19]: s = u'ＡＢＣＤＥＦＧ０１２３４５' * 10

In [20]: %time for n in range(1000000): mojimoji.zen_to_han(s)
CPU times: user 2.86 s, sys: 0.10 s, total: 2.97 s
Wall time: 2.88 s

In [21]: %time for n in range(1000000): unicodedata.normalize('NFKC', s)
CPU times: user 5.43 s, sys: 0.12 s, total: 5.55 s
Wall time: 5.44 s

In [22]: %time for n in range(1000000): zenhan.z2h(s)
CPU times: user 69.18 s, sys: 0.11 s, total: 69.29 s
Wall time: 69.48 s