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bamgineer
Bamgineer: Introduction of simulated allele-specific copy number variants into exome and targeted sequence data setsVisCap
VisCap is an open flexible, software program targeted to clinical laboratories for inference and visualization of germline copy number variants (CNVs) from targeted next-generation sequencing data. For algorithmic details, see Pugh TJ et al. Genet Med. 2016 Jul;18(7):712-9.ConsensusCruncher
ConsensusCruncher is a tool that suppresses errors in next-generation sequencing data by using unique molecular identifiers (UMIs) to amalgamate reads derived from the same DNA template into a consensus sequence.MEDIPIPE
fragmentomics
Collection of fragmentomic analysis scriptssu2c-gsc-scrna
Custom source code used in Richards, Whitley et al., Nature Cancer, 2021inspire-genomics
Pan-cancer analysis of genomic and immune landscape profiles of metastatic solid tumors treated with pembrolizumabcrescent
The CanceR Single Cell ExpressioN Toolkit one-line-command applications.crescent-frontend
CReSCENT Portal: https://crescent.cloud | CReSCENT Docs: https://pughlab.github.io/crescent-frontend/LFS-early-detection-ctdna
Multi-modal analysis of cell-free DNA for the early detection of cancer in Li-Fraumeni syndrome.oncographer
tracker
Generic research tracking systeminspire-ctdna
Custom R scripts for data visualization and statistical analysis for Bratman, Yang et al. 2020 Personalized circulating tumor DNA analysis as a predictive biomarker in solid tumor patients treated with pembrolizumabcancer-scrna-integration
A comparison of data integration methods for single-cell RNA sequencing of cancer samplescfMeDIP-seq-analysis-pipeline
Post-processing pipeline for next-generation circulating methylome data generated by cfMeDIP-seqpipeline-suite
Collection of pipelines for NGS analysis along with utilitiesLB-Seq
Liquid Biopsy Sequencing analysis tools for cell free DNA sequencingVisCapCancer
Tool for calling tumour-specific somatic copy number alterations from targeted sequencing data. This tool is based on the germline copy number variant caller published by Pugh TJ et al. Genet Med. 2016 Jul;18(7):712-9.TGL48_Uveal_Melanoma
scripts for uveal paperPughLabReadme
Documentation of best practices, coding tips, and ongoing projects developed by the Pugh Lab.BCa_ATACSEQ_Project
This repository contains custom code used for analysis in El Ghamrasni et al.,ctims
CTIMS projectped_CapTCRseq
Dynamics of peripheral T-cell repertoire in pediatric cancer patients over the course of chemoradiationwnt-medulloblastoma-singh
Code for scRNAseq analysis in Manoranjan et al., Nature Communications, 2020cbio_import_utils
ddx56-pearson-lab
Code for scRNAseq analysis in Pryszlak et al., Cell Reports, 2021Clump
net-seq
mcoder
HCC_cfMeDIP
TGL49_CHARM_LFS_Fragmentomics
cfmedip_analysis
Pre-processing pipeline to transform MEDIPS output wig files into matrix of chromosomal bins by samplesbtsc-glutaminase-weiss
Code for scRNAseq analysis in Restall et al., Cancer Research, 2020paper-inspire-cfmedip
Accompanying code for INSPIRE cfMeDIP-seq manuscriptLove Open Source and this site? Check out how you can help us