Discover ohdsi-studies/PandemicPrediction Open Source project

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Validating the COVID prediction models across time and databases

Covid19CharacterizationCharybdis

Characterizing Health Associated Risks, and Your Baseline Disease In SARS-COV-2 (CHARYBDIS) - a study to describe the baseline demographic, clinical characteristics, treatments and outcomes of interest among individuals tested for SARS-CoV-2 and/or diagnosed with COVID-19 compared to Influenza patients from 2017-2018

LegendT2dm

Covid19PredictionStudies

Development and validation OHDSI network studies for the covid19 prediction topic

HERACharacterization

Health equity research assessment (HERA) - a large scale characterization of gender and racial disparities

MentalHealthEquity

Assessing Health Equity in Mental Healthcare Delivery Using a Federated Network Research Model

Covid19HospitalizationCharacterization

Clinical Characterization of COVID-19

PioneerWatchfulWaiting

This study is part of the joint PIONEER - EHDEN - OHDSI studyathon in March 2021, and aims to advance understanding of clinical management and outcomes of watchful waiting in prostate cancer.

MethodsLibraryPleEvaluation

R code used to evaluate the OHDSI Methods Library for population-level estimation

Covid19EstimationHydroxychloroquine

Retrospective, real-world, observational study to estimate the population-level effects of hydroxychloroquine among patients with rheumatoid arthritis. Designed and executed during the OHDSI community COVID-19 virtual study-a-thon (March 26-29) to inform healthcare decision-making in response to the current global pandemic.

HowOften

[under development] Large-scale incidence characterization

HTML

DeepLearningComparison

Investigating different deep learning approaches

StudyRepoTemplate

A template for new study repositories

TeX

RanitidineCancerRisk

Cervello

Covid-19 pandEmic impacts on mental health Related conditions Via multi-database nEtwork: a LongitutinaL Observational study (CERVELLO)

BipolarMisclassificationValidation

OHDSI network study: external validation of a simple score model that predicts whether patients newly diagnosed with MDD actually have bipolar

AntiVegfKidneyFailure

BreastCancerBetweenScreen

WOO 2019 study: Predicting breast cancer within 3 years of a negative mammography

PCE

Network study validating the Pooled Cohort Equation Model

ConceptPrevalence

A package to calculate the counts of the standard and source concepts in an OMOP CDM and extract the current version of the mappings used.

TSQL

Covid19Icarius

Real-world, observational study to estimate the population-level effects of angiotensin converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARB) on coronavirus disease (COVID-19) incidence and complications

EvaluatingCardinalityMatching

This study aims to evaluate the performance of cardinality matching and large-scale propensity score matching at progressively smaller sample sizes and more stringent parameter settings among new users of ACEI vs. thiazide or thiazide-like diuretic monotherapy applying the framework set forth in the LEGEND-HTN study.

PhenotypePhebruaryCapr

Repo to store Capr implementations of all cohort definitions created during Phenotype Phebruary

DeadModel

A package for implementing the death imputation model on OMOP CDM data

PsmVsCm

Indirect covariate balance and residual confounding: an applied comparison of propensity score matching and cardinality matching

HIVTreatmentPathways

Corazon

Covid19SubjectsAesiIncidenceRate

Extending on our previous work by Li et al. in understanding the incidence rates of adverse events of special interest (AESI) for COVID-19, this work will look at the rates of these AESIs in patients who had COVDI-19 disease.

dGEMcovid

ScyllaCharacterization

The aim of this study is to characterize all emerging drug therapies used in COVID-19 treatment.

cmcEndoPcos

Study specifications from the DBMI/OHDSI/JNJ Study-a-thon on Women's Health.

HTML

MyositisNetworkStudy

OHDSI Network Study lead by John Hopkins Myositis Group

DistributedLMM

A distributed method for calculating pooled effect estimates applied to COVID-19 hospitalization

PORPOISE

PORPOISE research code and materials for training and validating ML models on the network of OMOP CDM databases.

EhdenCovidUseCase

The aim of this study is to estimate treatment effects for COVID-19 treatments using data from the EHDEN network and to combine these observational results with data from randomised studies.

MusculoskeletalAEsAfterAIs

A Population level estimate (PLE) cohort study with prior A Cohort Diagnostics study to determine the feasibility using non-identifiable data mapped to the OHDSI Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM) to evaluate the risk of adverse musculoskeletal events in post-menopausal women taking AI compared to tamoxifen to treat breast cancer.

EhdenRaDrugUtilization

Rheumatoid arthritis drug utilization (Barcelona Study-a-thon 2020)

NLP-Oncology

[under development] Redoing Karthik's cancer pathways study with and without NLP-derived histology data (mapped to cancer teminologies)

TeX

SemaglutideNaion

OHDSI network study for population-level effect estimation of risk of NAION and other vision disorders from exposure to semaglutide.

Eumaeus

Evaluating Use of Methods for Adverse Event Under Surveillance (for vaccines)

HTML

CovidSeverityPrediction

The algorithm to predict mortality and severe clinical outcome in patients with COVID-19

Ceeamos

OHDSI study to investigate the risk of schizophrenia in hypertensive patients using ACE inhibitor

Glp1ClrdEstimation

PhenotypePhebruary

EhdenRaPrediction

Prediction of clinical outcomes after methotrexate initiation

DMCharacterizationAP

TicagrelorVsClopidogrel

OHDSI network study: Net Adverse Clinical Event between Ticagrelor and Clopidogrel in Patients with Acute Coronary Syndrome

Covid19CohortEvaluation

A central package for evaluation the cohorts used in the various Covid-19 studies

PhenotypeLibraryDiagnostics

Computing cohort diagnostics for all cohort definitions in the OHDSI Phenotype Library

FluoroquinoloneAorticAneurysm

[under development]

MddAfterBbValidation

Covid19VaccinePrediction

A methodology study into the stability of prediction models across target cohort and outcome phenotypes

Covid19VaccineAesiDiagnostics

Covid19VaccineAesiIncidenceRate

Medon

Methods Evaluation of Durability in a Observational Network (MEDON).

TeX

VaccineEffectivenessEvaluation

Covid19DrugRepurposing

Evaluation of the safety (and where possible efficacy) of existing drugs considered for treatment of COVID-19.

ExistingStrokeRiskExternalValidation

A package for validating some previously published stroke models

COVID19CancerBaselineCharacterization

Future OHDSI network study to understand the baseline characteristics of cancer patients with COVID-19

OutcomeMisclassificationSysRev

Systematic review of outcome misclassification correction in pharmacoepidemiology

HTML

CauseSpecificMortality

Development of cause of death predictive model using Patient-level prediction

LegendT2dmEvidenceExplorer

LEGEND-T2DM Evidence Explorer

Covid19SusceptibilityAlphaBlockers

PceCohortDiagnostics

OT2DSI

Observational study of type 2 diabetes and its complications: a chronological overview using the OHDSI network

MultipleSclerosisBiologicsPml

[under development]

HTML

FeatureSelectionComparison

PatientLevelPrediction methods research investigating different feature selection approaches for simplifying models

TeX

EmptyStudyRepository

An empty repository, to be used as the template for new studies

EhdenRaDmardsEstimation

Retrospective, real-world, observational study to estimate the population-level effects of conventional synthetic disease-modifying antirheumatic drugs among patients with rheumatoid arthritis. Designed and executed at the EHDEN Study-a-thon in Barcelona, January 2020.

ScyllaEstimation

This OHDSI network study assesses the comparative effectiveness and safety among treatments administered during hospitalization and prior to intensive services. It also assesses the comparative effectiveness and safety among treatments administered after COVID-19 positive testing or diagnosis in the outpatient setting without prior hospitalization.

ReproducibilityRayJAMA2021

Reproducibility study of Ray et al JAMA 2021 comparative effectiveness of rivaroxaban vs apixaban in atrial fibrillation

CancerTxPathway

A package to extract chemotherapy records for cancer patients. The chemotherapy records are instantiated as Episode / Episode Event table with corresponding regimen as episode source concept id. The package also portrait the treatment patterns for patients with cancer and onset timing of the adverse event, i.e., neutropenia.

IbdCharacterization

Characterization study of inflammatory bowel disease

Covid19EstimationHydroxychloroquine2

Retrospective, real-world, observational study to estimate the population-level effects of hydroxychloroquine among patients with rheumatoid arthritis on select psychiatric and influenza outcomes. Designed during the OHDSI community COVID-19 virtual study-a-thon (March 26-29) to inform healthcare decision-making in response to the current global pandemic.

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