mahmoud/awesome-python-applications

Awesome Python Applications

Case studies in successfully shipping Python software

As developers, we spend our days with code. The site you're reading this on is mostly modules, packages, libraries, frameworks, and the like. But users see applications.

When building our own applications, open-source Python applications are a gold mine of practical patterns that we know work together. A production application is worth a thousand blog posts and Stack Overflow answers.

This document is an always-growing list of 410 open-source Python applications arranged by topic, with links to repositories, docs, and more, generated from structured data using apatite. If you have one to add or find some information missing, please let us know!

Read the announcement post to learn more about this list.
Subscribe to the RSS/Atom feed to see new applications added.

Contents

Internet (37)
Audio (17)
Video (7)
Graphics (20)
Games (10)
Productivity (25)
Organization (42)
Communication (35)
Education (8)
Science (24)
CMS (11)
ERP (5)
Static Site (9)
Dev (182)
1. SCM (17)
2. Code Review (5)
3. Storage (18)
4. Ops (28)
5. Security (30)
6. Docs (7)
7. Editor (13)
8. Package Managers (11)
9. Package Repositories (5)
10. Build (13)
11. Shell (3)
12. Other Dev projects (35)
Misc (13)

Internet

ArchiveBox - (Repo, Home, Docs) Self-hosted web archive, for creating local, browsable backups of content from the web. Imports HTML, JS, PDFs, video, subtitles, git repositories, and more, from Pocket, Pinboard, browser history, etc. (organization, linux, windows, docker)
archivematica - (Repo, Home, Docs) Digital preservation system designed to maintain standards-based, long-term access to collections of digital objects, targeted at archivists and librarians. (organization, server)
Bookwyrm - (Repo, Home) Social reading and reviewing, decentralized with ActivityPub. (organization, communication, server, django)
buku - (Repo, Fund, Docs) Browser-independent bookmark manager with CLI and web server frontends, with integrations for browsers, cloud-based bookmark managers, and emacs. (organization, linux, windows, mac, server)
Canto - (Repo, WP) RSS daemon and curses-based client. (linux, tui)
CTFd - (Repo, Home, Docs) CTFd is a Capture The Flag framework focusing on ease of use and customizability. It comes with everything you need to run a CTF and it's easy to customize with plugins and themes. (server)
Deluge - (Repo, Home, WP, Fund) Popular, lightweight, cross-platform BitTorrent client. (linux, windows, mac, server, gtk)
Elixire - (Repo, Home, Docs) Featureful file host and link shortener with API and support for multiple vanity urls. (server)
FlaskBB - (Repo, Home, Demo, Docs) A classic web forum application (bulletin board) with a modern look. (server)
gPodder - (Repo, Home) Simple, mature media aggregator and podcast client. (linux, windows, mac, gtk)
Grafana OnCall - (Repo, Docs) Developer-friendly incident response with brilliant Slack integration, with a PagerDuty migration path. (server, corp, django)
hosts - (Repo) Command-line application which merges reputable hosts files with deduplication for the purpose of blocking undesirable websites via DNS blackhole. (security, linux, windows, mac)
httpie - (Repo, Home, PyPI) Command-line HTTP client with JSON support, syntax highlighting, wget-like downloads, extensions, and more. (dev, linux, windows, mac)
Isso - (Repo, Home) Lightweight commenting server, designed as a drop-in replacement for Disqus. (server)
KindleEar - (Repo, Docs) Web application to automatically aggregate RSS into periodical mobi/epub files with images and send it to your kindle or your email. (server)
Mylar - (Repo) A web-based automated comic book downloader (cbr/cbz) for use with SABnzbd, NZBGet, and torrents. (graphics, linux)
Neubot - (Repo, Home) Lightweight agent which collects data for net-neutrality research. (linux, windows, mac)
NewsBlur - (Repo, Home) Web-based personal news reader. (server, django)
Newspipe - (Repo, Demo, gh, Docs) Web-based news aggregator and reader. (server)
nsupdate.info - (Repo, PyPI, Docs) Featureful dynamic DNS service, using the Dynamic DNS UPDATE protocol (RFC 2136) to update BIND and other major nameservers. (ops, server)
Nyaa - (Repo) Bittorrent tracker software built for anime site nyaa.si. (server)
Pi-Hole - (Repo, Home, WP) Linux network-level advertisement and internet tracker blocking application which acts as a DNS sinkhole, and (optionally) a DHCP server, intended for use on a private network. (linux, server)
Planet - (Repo, Home, WP) RSS and Atom feed aggregator, designed to collect posts from the weblogs of members of an Internet community and display them on a single page. Used to power Planet Python and many more. (server)
Pol - (Repo, Home) Web application which allows users to subscribe to changes on a web site via an autogenerated RSS feed. (server)
PostHog - (Repo, Home, Docs) Self-hostable product analytics for tracking events, visualizing funnels, and much more. (docker)
PyLoad - (Repo, Home) Download manager with a web interface and API. (linux, windows, mac)
Qute Browser - (Repo, Home) Keyboard-driven, minimal, vim-like browser based on PyQt5. (linux, windows, mac, qt5)
Reddit - (Repo, Home) Social news forum with voting, commenting, karma, and more. (Archival repo from 2017.) (server)
SABnzbd - (Repo, Home, Docs) Simple, cross-platform newsreader for downloading from Usenet. Supports many integrations and 16 languages. (linux, windows, mac, server)
Searx - (Repo, Docs) Self-hosted metasearch engine, aggregating results from more than 70 services while avoiding tracking and profiling. (security, server, flask)
speedtest-cli - (Repo, PyPI) Command-line interface for testing Internet bandwidth using speedtest.net. (console)
streamlink - (Repo, Home, PyPI) Command-line utility that extracts streams from various services and pipes them into a video player of choice. (linux, windows, mac)
syncserver - (Repo, Docs) All-in-one package for running a self-hosted Mozilla Firefox Sync server. (server)
Tribler - (Repo, Home, WP) Privacy enhanced BitTorrent client with P2P content discovery. (linux, windows, mac, qt5)
You-Get - (Repo, Home) Command-line program to browserlessly scrape and stream video, audio, and images from web sites. (linux, windows, mac)
youtube-dl - (Repo, Home, PyPI) Command-line program to browserlessly archive video and audio from YouTube and hundreds of other sites. (linux, windows, mac)
ZeroNet - (Repo, Home, WP, Docs) Open, free, and uncensorable websites, using Bitcoin cryptography and BitTorrent network. (linux, windows, mac)

Audio

Beets - (Repo, Home, PyPI) Feature-rich command-line music library manager with web UI, duplicate detection, transcoding, and tagging support, integrating with MusicBrainz, Discogs, and more. (linux, windows, mac)
Exaile - (Repo, WP) Cross-platform audio player, tag editor, and library organizer. (linux, windows, mac, gtk)
Frescobaldi - (Repo, WP) An editor for LilyPond music files. (linux, windows, mac, qt)
Friture - (Repo, Home) Visualizes and analyzes live audio data in real-time, including scope, spectrum analyzer, rolling 2D spectrogram, and more. (linux, windows, mac, qt5)
Funkwhale - (Repo, Home, Docs) Web-based, community-driven project that lets you listen and share music and audio within a decentralized, open network. (server)
GNU Radio - (Repo, Home, WP) Software development toolkit that provides signal processing blocks to implement software-defined radios and signal-processing systems. (linux, windows, mac, cpp, qt)
GNU Solfege - (Repo, WP) An ear-training program intended to help musicians improve their skills. (linux, windows, mac, gtk)
Mopidy - (Repo, Home) Extensible music player server with plugin support for a wide range of services. (server)
Music Player - (Repo, Home) A simple music player designed around an infinite intelligent playlist, with support for headless playback. (linux, mac)
MusicBrainz Picard - (Repo, Home, WP) Automatically identify, tag, and organize music albums and other digital audio recordings. (linux, windows, mac, qt)
PuddleTag - (Repo, WP) An audio tag (metadata) editor for audio file formats. (linux, qt4)
Quod Libet - (Repo, WP) Cross-platform audio player, tag editor, and library organizer. (linux, windows, mac, gtk)
SoundConverter - (Repo, WP) A GNOME-based audio file transcoder. (linux, gtk)
SoundGrain - (Repo, Home, Fund) Graphical interface designed for drawing and editing trajectories to control granular sound synthesis. (linux, windows, mac)
Stargate DAW - (Repo) All-in-one Digital Audio Workstation (DAW) with a suite of instrument and effect plugins. (linux, windows, mac, qt56)
Supysonic - (Repo) Implementation of the Subsonic server API, with support for browsing, streaming, transcoding, scrobbling, and more. (server)
Whipper - (Repo) A CLI-based CD Audio ripper designed for accuracy over speed, with support for overriding hardware caches, accuracy verification, MusicBrainz metadata lookup, hidden tracks, FLAC, and much more. (linux)

Video

Flowblade - (Repo, WP) Multitrack, non-linear video editing software for Linux. (linux, gtk)
Open Streaming Platform - (Repo) Self-hosted video streaming and recording server, designed as an alternative to Twitch and YouTube. (games, server)
OpenShot - (Repo, Home, WP, Fund) A cross-platform video editor for FreeBSD, Linux, macOS, and Windows. (linux, windows, mac, qt5)
Pitivi - (Repo, WP) Non-linear video editor for Linux, based on GStreamer. (linux, gtk)
Plumi - (Repo, WP) Video sharing content management system based on Plone. (cms, server, plone)
PyVideo - (Repo, Home) Static media index custom-built for the Python community, and all the content our meetings and conferences produce. (static_site, linux, server)
Vidcutter - (Repo) GUI and CLI aiming to be the fastest and simplest way to cut and join video. (linux, windows, mac)

Graphics

cartoonify / Draw This. - (Repo, Home) Turn a photograph into a toddler's drawing. Automatically! (console, docker, hardware)
Cura - (Repo, Home, WP, Docs) Popular desktop software for preparation and control of 3D printing, integrated with CAD workflows. (linux, windows, mac, corp, hardware)
DrawBot - (Repo, Home, WP) A powerful programmatic 2D drawing application for MacOS X which generates graphics from Python scripts. (education, dev, mac)
FreeCAD - (Repo, WP) General-purpose parametric 3D CAD modeler and a building information modeling (BIM) software with finite-element-method (FEM) support. (linux, windows, mac, cpp, qt)
Gaphor - (Repo, Docs) Simple UML modeling tool designed for beginners. (docs, linux, windows, mac, flatpak, gtk)
Lector - (Repo) Desktop ebook reader and browser, with support for many formats, including comic book archives. (linux)
MakeHuman - (Repo, WP) 3D computer graphics software designed for the prototyping of photo realistic humanoids. (linux, windows, mac, qt)
Meshroom - (Repo, Home) Photogrammetry pipeline, for turning photographs into 3D models. (linux, windows, mac, qt)
Mylar - (Repo) A web-based automated comic book downloader (cbr/cbz) for use with SABnzbd, NZBGet, and torrents. (internet, linux)
MyPaint - (Repo, Home, WP) Raster graphics editor for digital painters with a focus on painting rather than image manipulation. (linux, windows, mac, gtk)
NFO Viewer - (Repo, Home) A simple viewer for NFO files and the ASCII art therein, with preset fonts, encodings, automatic window sizing, and clickable hyperlinks. (misc, linux, windows)
OCRFeeder - (Repo, WP) An optical character recognition suite for GNOME, with support for command-line OCR engines like CuneiForm, GOCR, Ocrad and Tesseract. (linux, gtk)
OCRopus - (Repo, WP) Document analysis and optical character recognition (OCR) system. (linux, mac, console)
Octoprint - (Repo, Home, Fund) Web-based controller for consumer 3D printers. (server, flask, hardware)
PhotoCollage - (Repo) Automatically lays out a photo collage to fill out a given poster space. (linux, gtk)
Photonix - (Repo, Home, Demo) Web-based photo management, featuring smart filtering with object recognition, location awareness, color analysis, and more. (server)
Pynocchio - (Repo, Home) Minimalist comic reader, supporting many common image and archive formats. (linux)
Quru Image Server - (Repo, Home, Demo, Docs) High-performance web server for creating and delivering dynamic images. (server)
SK1 - (Repo, Home, WP) Feature-rich, cross-platform illustration program. (linux, windows, mac, gtk, wx)
Thumbor - (Repo, Home, Docs) Photo thumbnail service with resizing, flipping, and smart cropping of images. (dev, server)

Games

Cataclysm: Dark Days Ahead (Launcher) - (Repo, Home) Launcher for popular FOSS game CDDA, which supports automatic updates and mod management. (linux, windows, mac)
Frets on Fire X - (Repo) Highly customizable rhythm game supporting many modes of guitar, bass, drum, and vocal gameplay for up to four players. (linux, windows, pygame)
Lucas Chess - (Repo, Home) Featureful chess client for Windows, with some Linux support. (linux, windows, qt4)
Lutris - (Repo, Home, WP, Fund) Gaming platform for GNU/Linux, managing game installations with a unified interface. (linux, gtk)
Open Streaming Platform - (Repo) Self-hosted video streaming and recording server, designed as an alternative to Twitch and YouTube. (video, server)
PyChess - (Repo, Home, WP) Advanced chess client, suitable for new, casual, and competitive play. (linux, windows, gtk)
Pyfa - (Repo) Python Fitting Assistant, cross-platform experimentation tool for EVE Online ship fittings. (linux, windows, mac)
PySolFC - (Repo, Home, Android) Highly-portable collection of solitaire card games. (linux, windows, android, kivy, tk)
term2048 - (Repo, PyPI) TUI version of 2048. (linux, mac, tui)
Unknown Horizons - (Repo, Home) 2D real-time strategy simulation with an emphasis on economy and city building. (Not unlike Age of Empires) (linux, windows, mac)

Productivity

Autokey - (Repo, WP, PyPI) Desktop automation utility for Linux and X11. (linux, gtk, qt)
Bleachbit - (Repo, Home) System cleaner designed to free disk space and maintain privacy. (linux, windows, gtk)
BorgBackup - (Repo, Home) Deduplicating backup system with optional encryption and other features. (linux)
Bup - (Repo, Home) Efficient backup system based on the git packfile format, providing fast incremental saves and global deduplication. (linux, mac)
Excalibur - (Repo) Web interface to extract tabular data from PDFs. (linux, windows)
Glances - (Repo, Home, Docs) A cross-platform top/htop alternative, providing an overview of system resources. (ops, linux, windows, mac, server)
gmvault - (Repo, Home) Tool for backing up gmail accounts. (linux, windows, mac, qt5)
Gridsync - (Repo) Cross-platform GUI built to synchronize local directories with Tahoe-LAFS storage grids. (storage, linux, windows, mac)
GTimeLog - (Repo, Home, Fund, Docs) Desktop-based time tracker with support for logging billable/non-billable work. (organization, linux, windows, mac)
Kibitzr - (Repo, Home, PyPI, Docs) Self-hosted personal assistant server for automating routine tasks. (server)
Mackup - (Repo, PyPI) Utility to back up and synchronize application settings, with support for several storage backends (e.g., Dropbox, Git), and dozens of applications. (linux, mac)
Metamorphose - (Repo, Home) Graphical mass renaming program for files and folders. (linux, windows, mac, wx)
Nuxeo Drive - (Repo, Home, Docs) Cross-platform desktop synchronization client for the Nuxeo platform. (storage, linux, windows, mac, console, appimage, lgpl, qt5)
nvda - (Repo, Home) Non-Visual Desktop Access, a powerful screen reader for Windows. (windows, wx)
OCRmyPDF - (Repo, Fund, Snap, Docs) Adds an OCR text layer to scanned PDF files, enabling text search and selection. (console)
Plover - (Repo, Home, Fund, Docs) Background service for automatic translation of stenography movements to keystrokes, enabling typing speeds in excess of 200WPM in any application. (linux, windows, mac, hardware, qt5)
Psono - (Repo, Home, Demo, Docs) Server-based password manager, built for teams. (security, server)
Ranger - (Repo, Home) TUI (Text User Interface) file manager, inspired by vim. (linux, tui)
Redash - (Repo, Home) Data visualization and dashboard construction geared toward business intelligence, used by Mozilla, SoundCloud, Sentry, and others. (server, flask)
ReproZip - (Repo, Home, Demo, PyPI, Docs) Command-line tool which automatically builds reproducible experiments archives from console commands, designed for use in computational science. (science, linux)
Sunflower - (Repo, Home) Small and highly-customizable twin-panel file manager for Linux with plugin support. (linux)
Superset - (Repo, Docs) Data exploration, visualization, and business intelligence web application. (server)
VisiData - (Repo, Home, Fund, PyPI, Docs) Interactive multitool for exploring, analyzing, and converting datasets in the terminal. (linux, mac, tui)
Vorta - (Repo, Home) GUI backup client built on top of BorgBackup. (linux, mac)
wttr.in - (Repo, Home) Weather forecast service that supports various representations, suitable for the terminal or web browser. (server, flask)

Organization

Ambar - (Repo, Home, Demo, Docs) Document search engine with automated crawling, OCR, tagging, and instant full-text search. (server)
ArchiveBox - (Repo, Home, Docs) Self-hosted web archive, for creating local, browsable backups of content from the web. Imports HTML, JS, PDFs, video, subtitles, git repositories, and more, from Pocket, Pinboard, browser history, etc. (internet, linux, windows, docker)
archivematica - (Repo, Home, Docs) Digital preservation system designed to maintain standards-based, long-term access to collections of digital objects, targeted at archivists and librarians. (internet, server)
Baby Buddy - (Repo, Demo) Mobile-friendly web application which helps caregivers track sleep, feedings, diaper changes, and tummy time to learn about and predict baby's needs without (as much) guesswork. (server)
Baserow - (Repo, Home, gh, Docs) Web-based no-code persistence platform, like a database meets a spreadsheet, with a REST API. (storage, server, django)
beancount - (Repo, Home, gh, PyPI, Docs) A double-entry bookkeeping language to define financial transaction records in plain text, then generate a variety of reports, via CLI and web interface. (See also, Plain Text Accounting). (linux, windows, mac)
Bookwyrm - (Repo, Home) Social reading and reviewing, decentralized with ActivityPub. (internet, communication, server, django)
buku - (Repo, Fund, Docs) Browser-independent bookmark manager with CLI and web server frontends, with integrations for browsers, cloud-based bookmark managers, and emacs. (internet, linux, windows, mac, server)
Byro - (Repo, Docs) Web-based membership administration tool for small and medium sized clubs/NGOs/associations of all kinds, with a focus on the DACH region. (server)
Calibre - (Repo, Home, WP, Fund) E-book manager designed for viewing, converting, editing, and cataloging e-books in all major formats. (linux, windows, mac, qt5)
Calibre-Web - (Repo) Web application providing a clean interface for browsing, reading, and downloading ebooks using an existing Calibre database. (linux)
CherryTree - (Repo, Home) Hierarchical wiki-like personal notepad, featuring rich text and syntax highlighting. (linux, windows, gtk)
Collaborate - (Repo, Docs) Web-based collaboration tool designed by Propublica for newsrooms to share datasets, with a workflow built around assigning tips and maintaining contacts. (communication, server)
CouchPotato - (Repo, Home) Personal video recorder focused on movies, with support for usenet and torrents. (linux, windows, mac)
dupeGuru - (Repo, Home, Docs) Cross-platform GUI tool to find duplicate files. (linux, windows, mac)
dvc (Data Version Control) - (Repo, Home, Docs) Command-line tool for version control over data used in machine learning projects. Aims to replace Excel and other tools used to track and deploy model versions. (scm, linux, windows, mac)
fava - (Repo, Demo, Docs) Web interface for the double-entry bookkeeping software Beancount with a focus on features and usability. (linux, windows, mac)
Gramps - (Repo, Home) Genealogy software that is both intuitive for hobbyists and feature-complete for professional genealogists. (linux, windows, mac, gtk)
GTimeLog - (Repo, Home, Fund, Docs) Desktop-based time tracker with support for logging billable/non-billable work. (productivity, linux, windows, mac)
Headphones - (Repo, Docs) Web-based digital music library for automating music downloads through Usenet and torrents. (linux, windows, mac)
ihatemoney - (Repo, Home, Docs) Web application made to ease shared budget management by keeping track of who bought what, when, and for whom. (server)
Indico - (Repo, Home, Demo, Docs) Feature-rich web application designed at CERN for managing events, with support for conference organization workflow, from content management to receiving and reviewing abstracts/papers, event registration, payment integration, room booking, and more. (communication, server)
Invenio - (Repo, Docs) Customizable platform for running a trusted digital repository. (linux)
jrnl - (Repo, Home) Simple, ecncrypted journal application for your command line. (linux, windows, mac, homebrew)
LazyLibrarian - (Repo, Forum, Docs) Web-based digital library organizer with support for following authors and automatic metadata retrieval. (linux, mac)
Mayan - (Repo, Home, Fund, PyPI, Docs) Web-based document management system, designed to store, introspect, and categorize files, with OCR, preview, label, signing, and sending capabilities. Also featuring workflow system, role-based access control, and REST API. (server)
MLflow - (Repo, Home, Docs) Integrated command-line application and web service, supporting an end-to-end machine-learning workflow around tracking, packaging, and deploying. Developed by Databricks. (dev, linux, mac, corp)
OpenLibrary - (Repo, Home, WP) Web application for an open, editable library catalog, used by The Internet Archive towards building a web page for every book ever published. (linux, windows, mac, docker)
Paperless - (Repo, Docs) Scan, index, and archive all of your paper documents. Supports OCR, tags, search, encryption and more. (server)
Paperwork - (Repo, Home, Fund, Docs) Personal document manager for organizing scanned documents and PDFs, with support for OCR, automatic tagging, and search. (linux, windows, gtk)
Pinry - (Repo, Home, Docs) Tiling image board system for saving, tagging, and sharing images, videos, and websites, like a self-hosted Pinterest. (docker, server)
Pretalx - (Repo, Home, Fund) Web-based conference planning tool, with support for Calls for Papers (CFP), scheduling, and speaker management. (communication, server)
PyMedusa - (Repo, Home) Video library manager for TV shows, with automatic download support. (linux, windows)
Radicale - (Repo, Home) Simple CalDAV (calendar) and CardDAV (contact) server. (server)
RedNotebook - (Repo, Home) Desktop journal designed for rich text, media, and template-based entries, which can be tagged and searched, as well as exported to plain text, HTML, Latex, or PDF. (linux, windows, mac)
Scholia - (Repo, Home, Docs) Python package and web application for interacting with scholarly information on Wikidata. (science, server)
Senaite - (Repo, Home) Web-based, mobile-first laboratory information management system (LIMS). (server)
SiCKRAGE - (Repo, gh, Docs) Video library manager with support for automatic TV show archival. (linux, windows)
Taiga - (Repo, Home, Docs) Web application built for managing projects with agile development processes. (dev, server, django)
Wikid Pad - (Repo, Home) Desktop wiki notebook for storing your thoughts and ideas. (linux, windows, mac, wx)
Xandikos - (Repo, Home) Lightweight but relatively complete CardDAV/CalDAV server which backs up changes in a Git repository. (server)
Zim Wiki - (Repo, Home) Desktop wiki designed for note-taking, list-making, and drafting. (linux, windows, gtk)

Communication

Abilian SBE - (Repo, Home) A "Social Business Engine" with features including lightweight document management, discussions, wikis, timelines, and more. (cms, server)
Askbot - (Repo, Home) Q&A web platform similar to StackOverflow, complete with tagging, reputation, badges, and more. (server, corp)
Bitmessage - (Repo, Docs) Reference client for Bitmessage, a peer-to-peer encrypted decentralised communication protocol. (linux, windows, mac, kivy, qt4, tui)
Bookwyrm - (Repo, Home) Social reading and reviewing, decentralized with ActivityPub. (internet, organization, server, django)
Collaborate - (Repo, Docs) Web-based collaboration tool designed by Propublica for newsrooms to share datasets, with a workflow built around assigning tips and maintaining contacts. (organization, server)
dak - (Repo) Collection of programs used to maintain the Debian project's email archives. (linux)
Django Wiki - (Repo, Demo, Docs) A simple and mature web-based wiki. (server)
Docassemble - (Repo, Home, Docs) Platform for creating mobile-friendly web-based interviews, collecting responses, and much more. (server)
Formspree - (Repo, Home) Web server which turns an HTML form submission into an email, without registration, JavaScript, or custom Python. (server, corp)
Gajim - (Repo, WP) Lightweight, cross-platform instant messaging client for the XMPP protocol. (linux, windows, mac, gtk)
GlobaLeaks - (Repo, Home) Web application to enable secure and anonymous whistleblowing initiatives. (server)
Hangups - (Repo, Snap, Docs) Third-party instant messenger for Google Hangouts, with support for group messaging and other proprietary features. (linux, mac, docker, snap)
Hawkpost - (Repo, Home) Web application which enables receiving encrypted messages from less technical senders. (server)
Helios Voting - (Repo, Home) End-to-end verifiable voting system. (server)
Inboxen - (Repo, Home, Docs) Web application which provides an infinite number of unique email inboxes, for segmenting services and maintaining privacy. (server)
Indico - (Repo, Home, Demo, Docs) Feature-rich web application designed at CERN for managing events, with support for conference organization workflow, from content management to receiving and reviewing abstracts/papers, event registration, payment integration, room booking, and more. (organization, server)
Magic Wormhole - (Repo, PyPI, Docs) Security- and speed-focused file transfer tool with support for files, text, and directories. (linux, mac, console)
Mailman - (Repo, Home, WP) The original listserv, a web application and email server for managing subscriptions and discussion archives. (server)
Mailpile - (Repo, Home) Fast email client with user-friendly encryption and privacy features. (linux, windows, mac)
Mailu - (Repo, Home) Full-featured mail server designed for easy setup and maintenance, supporting IMAP, IMAP+, SMTP, and Submission, as well as a slew of advanced features. (server)
Moa Bridge - (Repo, Home) A service to cross post Mastodon toots to Twitter and Instagram. (server, flask)
Modoboa - (Repo, Home) Mail hosting and management platform including web UI based on Django. Provides useful components such as an admin panel and webmail. Integrates with Postfix or Dovecot. (server)
MoinMoin - (Repo, Home, WP, Docs) Python's own web-based wiki software, used for the official Python wiki and many others. (server)
OfflineIMAP - (Repo, Home, WP) IMAP reader and synchronizer. (linux)
OnionShare - (Repo, Home, Docs) Secure and anonymous file sharing over Tor services. (linux, windows, mac, qt5)
Pootle - (Repo, Home, WP) Web application for collaborative translation. (server)
Pretalx - (Repo, Home, Fund) Web-based conference planning tool, with support for Calls for Papers (CFP), scheduling, and speaker management. (organization, server)
pycsw - (Repo, WP) Full implementation of the OpenGIS Catalogue Service Implementation Specification. (server)
RapidSMS - (Repo, Home, Docs) Interactive SMS text messaging platform. (server)
SecureDrop - (Repo, Home, Docs) Whistleblower submission system for media organizations to securely accept documents from anonymous sources. Originally created by Aaron Swartz and currently managed by the Freedom of the Press Foundation. (server, flask)
Socialhome - (Repo, Home, gh, Docs) Web application enabling users to build a federated personal profile with social networking functionality. (server)
Synapse - (Repo, Home, Fund) Reference server for the matrix.org distributed chat protocol. Used daily by tens of thousands at riot.im. (server)
Virtaal - (Repo, Home) Cross-platform GUI for performing translation, with support for a variety of formats. (linux, windows, mac, gtk)
Weblate - (Repo, Home, PyPI) Web based localization tool with tight version control integration. (server)
Zulip - (Repo, Home, WP, Docs) Powerful chat server and web client with support for threaded conversations. (server)

Education

Anki - (Repo, Home, Docs) Powerful desktop application for flash cards and memorization. (linux, windows, mac, qt5)
DrawBot - (Repo, Home, WP) A powerful programmatic 2D drawing application for MacOS X which generates graphics from Python scripts. (graphics, dev, mac)
Kolibri - (Repo, Home, Demo, PyPI, Docs) Self-hostable learning web application targeted at making high quality education technology available in low-resource communities (e.g., rural schools, refugee camps, orphanages, non-formal school systems, and prison systems). (server)
Mnemosyne - (Repo, Home) Spaced-repetition flashcard program for efficient memorization. (linux, windows, mac, qt5)
NBGrader - (Repo, Docs) Jupyter-based application which enables educators to create, assign, and grade assignments in notebook form. (server)
Open edX Platform - (Repo, Home, WP) Platform for online education providers, powering edX. (server)
RELATE - (Repo, Docs) Web-based courseware with support for course planning and versioning, scheduling, testing, and grading. (server)
Tutor - (Repo, Docs) Docker-based Open edX distribution, both for production and local development, with a goal of easing deployment, customization, upgrading, and scaling. (server)

Science

AnuGA - (Repo) Advanced simulation of the shallow water equation, for modeling tsunamis, dam breaks, and floods. (linux, windows)
Artisan - (Repo, Home, Docs) Desktop visual scope for coffee roasters, which helps coffee roasters record, analyze, and control roast profiles. (linux, windows, mac)
ASCEND - (Repo, Home, WP) Mathematical chemical process modelling system developed at Carnegie Mellon University since late 1978. (linux, windows, mac, gtk)
CellProfiler - (Repo, Home, Manual, Docs) Interactive data exploration, analysis, and classification of biological image sets. (linux, windows, mac)
cellxgene - (Repo, Home) Web-based interactive explorer for single-cell transcriptomics data. (linux, windows, mac, fnd)
CKAN - (Repo, Home) Data management system (DMS) which makes it easy to publish, share, and use data. Data hubs powered by CKAN include datahub.io, catalog.data.gov, and europeandataportal.eu, among many other sites. (server, flask)
CoCalc - (Repo, Home, WP) Collaborative calculation in the cloud, with support for the scientific Python stack, SageMath, R, LaTeX, Markdown, and more. Also features chat, course management, and other supporting functionality. (server)
Dissem.in - (Repo, Home, Docs) Web platform to help researchers upload their papers to open-access repositories. (server, django)
Galaxy - (Repo, Home, Docs) Web-based platform for reproducible and transparent computational research, with a focus on bioinformatics. (server)
InVesalius - (Repo, Home, WP) Generates virtual reconstructions of structures in the human body for medical purposes, including CT and MRI scans. (linux, windows, mac, gtk)
Manim - (Repo, Docs) Animation engine for explanatory math videos, primarily designed for works by 3blue1brown. (linux)
Mayavi - (Repo, Home) General purpose, cross-platform tool for 2-D and 3-D scientific data visualization. (linux, windows, mac, qt4)
Mosaic - (Repo, Home, Docs) Desktop-based single molecule analysis toolbox that automatically decodes multi-state nanopore data. (linux, windows, mac, gov)
odemis - (Repo, Home) Desktop imaging workflow software for Delmic microscopes, supporting autofocus, coordinate history, and OME-TIFF and HDF5 export. (linux)
OPEM - (Repo, Docs) A modeling tool for evaluating the performance of proton exchange membrane (PEM) fuel cells. (linux, windows, mac)
Orange - (Repo, Home, WP) Component-based data mining software for graphical interactive data analysis and visualization. (linux, windows, mac, qt4, qt5)
Pybliographer - (Repo, Home) Bibliographic database manager with a user-friendly desktop UI. (linux, gtk)
ReproZip - (Repo, Home, Demo, PyPI, Docs) Command-line tool which automatically builds reproducible experiments archives from console commands, designed for use in computational science. (productivity, linux)
Sage Math - (Repo, Home, WP) Cross-platform computer algebra system with features covering many aspects of mathematics, including algebra, combinatorics, graph theory, numerical analysis, number theory, calculus, and statistics. (linux, windows, mac)
Scholia - (Repo, Home, Docs) Python package and web application for interacting with scholarly information on Wikidata. (organization, server)
SOFA Statistics - (Repo, Home) User-friendly statistics and analysis with a learn-as-you-go approach. (linux, windows, mac, wx)
Spack - (Repo, Home, Docs) Language-independent package manager for supercomputers, Mac, and Linux, designed for scientific computing. (pkg_mgr, linux, mac)
Taguette - (Repo, Home, gh, PyPI, Docs) Web-based qualitative research tool supporting importing, tagging, highlighting, and exporting many document formats. (server)
Veusz - (Repo, Home) 2D and 3D scientific plotting, designed to produce publication-ready PDF or SVG graphs. (linux, windows, mac, qt)

CMS

Abilian SBE - (Repo, Home) A "Social Business Engine" with features including lightweight document management, discussions, wikis, timelines, and more. (communication, server)
Django-CMS - (Repo, Home) Enterprise content management system based on the Django framework with version control, multi-site support, and more. (server, django)
Ella - (Repo, Docs) Django-based content management system with a focus on high-traffic news sites and Internet magazines. (server, django)
Mezzanine - (Repo, Home) Consistent and flexible content management platform built on the Django framework. (server, django)
Plone - (Repo, Home, WP) Extensible enterprise content management system built on Zope. (server)
Plumi - (Repo, WP) Video sharing content management system based on Plone. (video, server, plone)
Pretix - (Repo, Home, Blog, PyPI, Docs) Web-based ticketing software, with support for customizable storefronts, direct payments, box office, and reporting. (server, corp)
PyCon - (Repo, Home, Docs) Content management and conference organization web application, based on Django and Symposion. (server, django)
Saleor - (Repo, Home) Modular, high-performance e-commerce storefront built with Django, GraphQL, and ReactJS. (server, django)
Shuup - (Repo, Home, Docs) Storefront web application, with support for single- and multi-marketplace models. (server)
Wagtail - (Repo, Home) A Django content management system focused on flexibility and user experience. (server, django)

ERP

ERP5 - (Repo, Home, WP) Web-based ERP, CRM, DMS, and Big Data system with hundreds of built-in modules, designed for corporate scalability. (server)
ERPNext - (Repo, Home, WP) Web-based ERP system with accounting, inventory, CRM, sales, procurement, project management, and HR. Built on Frappe and MariaDB. (server)
Frepple - (Repo, Home, Docs) Web-based supply chain planning for production planning and scheduling. (linux, server)
Odoo - (Repo, Home, WP) Web-based ERP and CRM with many built-in modules, plus thousands of apps to suit any business. (server)
Tryton - (Repo, Home, WP, Docs) Modular web-based ERP, designed for companies of all sizes. (server, fdn)

Static Site

Cactus - (Repo, PyPI) Static website generator using Django templates. (linux, windows, mac)
Chert - (Repo, PyPI) Static site generator with built-in support for listicles, created by this humble author, used to power calver.org, 0ver.org, and sedimental.org, the author's blog. Mostly here as an easter egg :) (linux, windows, mac)
Grow - (Repo, Home, PyPI) Static site generator optimized for building interactive, localized microsites, with a focus on workflow and maintainability. (linux, windows, mac)
Hyde - (Repo, Home, PyPI) Static site generator which began as the Python counterpart to Jekyll. (linux, windows, mac)
Lektor - (Repo, Home, PyPI) Static site generator with built-in admin console and minimal desktop application. (linux, windows, mac)
Nikola - (Repo, Home, PyPI) Command-line static site generator with incremental rebuilds and support for Markdown, reST, Jupyter notebooks, and HTML. (linux, windows, mac)
Pelican - (Repo, Home, PyPI) Command-line static site generator that supports Markdown and reST syntax. (linux, windows, mac)
Prosopopee - (Repo, Demo, PyPI, Docs) A static site generator designed for photographers and others who tell stories with pictures. (linux, windows, mac)
PyVideo - (Repo, Home) Static media index custom-built for the Python community, and all the content our meetings and conferences produce. (video, linux, server)

Dev

Projects related to software development and adjacent technical areas.

SCM

Allura - (Repo, Home, WP) Software forge, with support for git, hg, and svn. (server)
dvc (Data Version Control) - (Repo, Home, Docs) Command-line tool for version control over data used in machine learning projects. Aims to replace Excel and other tools used to track and deploy model versions. (organization, linux, windows, mac)
Git Cola - (Repo, Home) Featureful cross-platform GUI wrapper for git. (linux, windows, mac, qt4, qt5)
Gitless - (Repo, Home, PyPI, Docs) Simple version control system built on top of Git. (linux, windows, mac)
GNU Bazaar - (Repo, Home, WP, Docs) Distributed and client-server revision control system. (linux, windows, mac)
Kallithea - (Repo, WP) Software forge for Mercurial and Git with a built-in push/pull server, full text search, and code-review. Forked from RhodeCode in 2014. (server)
Klaus - (Repo, Demo, PyPI, Docs) pip-installable web-based viewer for git repositories that "just works". (server)
Launchpad - (Repo, Home, WP, Docs) Software forge designed and run by Canonical, with support for Git and Bazaar. (server)
Mercurial - (Repo, Home, WP) Cross-platform distributed revision-control system designed for high performance and advanced branching/merging capabilities. (linux, windows, mac)
Pagure - (Repo, Home) Software forge focused on git and developed by the Fedora engineering team. (server)
Patchwork - (Repo, Home, Docs) Web-based patch tracking system designed to facilitate code contribution to an open-source project. Designed and used for Linux kernel subsystem development. (server)
RabbitVCS - (Repo, Home, Docs) Tools providing straightforward graphical access to Subversion or Git within a variety of clients, including as Nautilus, Thunar, Nemo, Caja, and the command line. (linux)
RhodeCode - (Repo, Home, WP) Self-hosted platform for behind-the-firewall source code management, providing centralized control over Git, Mercurial, and Subversion. (server, corp)
Roundup Issue Tracker - (Repo, Home, WP, gh) Highly-customizable issue tracking system featuring command-line, web, and email interfaces, historically used by the official Python bug tracker at bugs.python.org. (server)
TortoiseHg - (Repo, Home, Docs) Windows shell extension and a series of applications for the Mercurial distributed revision control system. Also includes GNOME and CLI support. (linux, windows, qt4, qt5)
Trac - (Repo, Home, WP, Docs) Enhanced web-based wiki and issue tracking system for software development projects. (server)
ViewVC - (Repo, Home) Browser interface for CVS and Subversion version control repositories. (server)

Code Review

Diffoscope - (Repo, Home, Demo, PyPI) Web-based deep comparison of files, archives, and directories, including support for diffing tarballs, ISO images, and PDFs. (server)
Meld - (Repo, Home) Visual diff and merge tool targeted at developers, providing two- and three-way comparison of both files and directories, and supports many version control systems including Git, Mercurial, Bazaar, and Subversion. (linux, windows, mac, gtk)
Review Board - (Repo, Home) Extensible code review tool for projects and companies of all sizes. (server)
Rietveld - (Repo, Home, WP) Django-based collaborative code review tool for Subversion written by Guido van Rossum to run on Google AppEngine. The basis for Gerrit. (server)
SQLFluff - (Repo, Home, Fund, PyPI) Dialect-flexible and configurable SQL linter, designed with ELT applications in mind, with support for templating and autofixing errors. (console)

Storage

B2 - (Repo, PyPI) Command-line tool that gives easy access to all of the capabilities of Backblaze's B2 Cloud Storage. (linux, windows, mac, corp)
Barman - (Repo) Remote backup and disaster recovery for PostgreSQL. (linux)
Baserow - (Repo, Home, gh, Docs) Web-based no-code persistence platform, like a database meets a spreadsheet, with a REST API. (organization, server, django)
Datasette - (Repo, PyPI, Docs) A tool for exploring and publishing data, backed by SQLite. (server)
EdgeDB - (Repo, Home, Docs) High-performance object-relational database built on top of PostgreSQL, featuring strict, strong typing, built-in migrations, and GraphQL support. (server)
FreeNAS - (Repo, Home, Docs) Operating system designed to be installed virtually any hardware platform, for sharing ZFS-based storage over a network, using SMB, NFS, AFP, FTP, and more. (server)
Gridsync - (Repo) Cross-platform GUI built to synchronize local directories with Tahoe-LAFS storage grids. (productivity, linux, windows, mac)
kinto - (Repo, Home, Docs) A generic JSON document store with sharing and synchronisation capabilities, supporting in-memory and PostgreSQL backends. (server)
mycli - (Repo, Home, PyPI) Interactive MySQL client that does auto-completion and syntax highlighting. (linux, mac)
Nuxeo Drive - (Repo, Home, Docs) Cross-platform desktop synchronization client for the Nuxeo platform. (productivity, linux, windows, mac, console, appimage, lgpl, qt5)
pgcli - (Repo, Home, PyPI) Interactive PostgreSQL client that does auto-completion and syntax highlighting. (linux, mac)
s3ql - (Repo, Docs) A standards-conforming, full-featured UNIX filesystem for cloud-based storage services (S3, Google Storage, OpenStack), supporting compression, encryption, deduplication, snapshotting, and more. (linux)
Seafile - (Repo, WP) Cross-platform file hosting and synchronization system. (server)
sqlmap - (Repo, Home, PyPI, Docs) Automatic SQL injection and database takeover. (security, console)
TahoeLAFS - (Repo, Home, WP) Decentralized cloud storage system for robust distributed data storage. (linux, windows, mac)
WAL-E - (Repo) Continuous archiving of PostgreSQL WAL files and base backups. (linux)
ZEO - (Repo, PyPI, Docs) Server and client providing ZODB-based storage over the network. (linux, server)
ZFSp - (Repo) A reverse-engineered ZFS implementation, written in Python, without reading the original C. (linux)

Ops

Airflow - (Repo, Docs) A platform to programmatically author, schedule and monitor workflows. (linux, server, corp, flask)
Ajenti - (Repo, Home, PyPI, Docs) Web-base server admin panel for fast, extensible remote access, featuring a web terminal, text editor, file manager, and more. (server)
Ansible - (Repo, Home, Docs) Agentless, playbook-based automation. (linux, mac, corp)
aws-cli - (Repo, PyPI, Docs) Official command-line interface for Amazon Web Services. (console, py26)
Beaker - (Repo, Home, Docs) Hardware integration testing system, used by RedHat to test compatiblity for RHEL and Fedora. (server, flask)
Cobbler - (Repo, Home, WP) Linux installation server that allows for rapid setup of network installation environments. (linux, server)
DCOS - (Repo, Home, WP, Docs) Management platform for hardware and software resources in datacenters, built on Apache Mesos. (server, corp)
fail2ban - (Repo, Home, WP) Daemon to ban hosts that cause multiple authentication errors on Linux servers. (linux, server)
Ganeti - (Repo) Virtual machine cluster management tool built on existing virtualization technologies such as Xen and KVM. (linux, server, haskell)
Glances - (Repo, Home, Docs) A cross-platform top/htop alternative, providing an overview of system resources. (productivity, linux, windows, mac, server)
Gunicorn - (Repo, Home, PyPI) Pluggable, pre-fork WSGI server, started as the counterpart to Unicorn. (server)
Healthchecks - (Repo, Home, Docs) Web-based monitor for scheduled jobs (e.g., cron). (server, corp)
Iris - (Repo, Home) Flexible automated incident paging system, developed by and used at LinkedIn. (server, corp)
Nagstamon - (Repo, Home, Docs) Status monitor for the desktop, with support for Nagios, Icinga, Opsview, and more. (linux, windows, mac)
NColony - (Repo, Home) Process manager and monitor. (linux, mac, server)
netbox - (Repo, Docs) IP address management (IPAM) and data center infrastructure management (DCIM) tool, conceived at Digital Ocean. (server, django)
nsupdate.info - (Repo, PyPI, Docs) Featureful dynamic DNS service, using the Dynamic DNS UPDATE protocol (RFC 2136) to update BIND and other major nameservers. (internet, server)
Oncall - (Repo, Home) Calendar tool designed for on-call management and scheduling, developed by and used at LinkedIn. (server, corp)
OpenStack - (Repo, Home, Docs) Cloud operating system that controls large pools of compute, storage, and networking resources throughout a datacenter, manageable through a web-based dashboard. (server, corp)
Pulp - (Repo, Home, Docs) Platform for managing repositories of software packages and making it available to a large numbers of consumers. Developed and used by Red Hat. (server)
Ralph - (Repo, Home, Docs) Simple and powerful Asset Management, DCIM, and CMDB system for the data center and back office. (server, django)
RDPY - (Repo) An implementation of the Microsoft Remote Desktop Protocol built on Twisted, including applications for client use, MITM proxy, and Honeypot server. (security, linux, windows, server)
Salt Stack - (Repo, Home) Automation for the management and configuration of any infrastructure or application at scale. (server, corp)
Shinken - (Repo, Home) Shinken is a modern, Nagios-compatible monitoring framework, designed to scale for large environments. (server)
SpaceSiren - (Repo, Docs) Honeypot management and alert system for AWS tokens, with a fully serverless architecture. (security, server)
Spinnaker - (Repo, Home, WP, Docs) Continuous delivery platform developed for Netflix's deployment and management of applications in cloud environments. (server, corp)
StackStorm - (Repo, Home) Rules- and event-driven operational automation for auto-remediation, security responses, troubleshooting, deployments, and more. (server, corp)
Supervisor - (Repo, Home) Process manager and monitor. (linux, mac, server)

Security

BYOB (Build Your Own Botnet) - (Repo) Client-server framework (RAT and C2 server) for security researchers to build and operate basic botnets. (linux, windows, mac)
CAPE - (Repo, Demo) Web application designed to automate malware analysis, succeeded by CAPEv2. (server)
CAPEv2 - (Repo, Demo) Web application designed to automate malware analysis, with a goal of extracting payloads and configuration from uploaded artifacts. (server)
Cowrie - (Repo, Home) Medium interaction SSH and Telnet honeypot designed to log brute force attacks and the shell interaction performed by the attacker. (server, corp)
detect-secrets - (Repo) An enterprise-friendly CLI for auditing, detecting, and preventing secrets in code. (dev, linux, windows, mac)
GRR Rapid Response - (Repo, Docs) Server-agent system focused on remote live forensics for quick, browser-based triage and analysis of attacks on fleets of machines, with agent support for Linux, Windows, and OS X. (server, corp)
hosts - (Repo) Command-line application which merges reputable hosts files with deduplication for the purpose of blocking undesirable websites via DNS blackhole. (internet, linux, windows, mac)
Hubble - (Repo, Docs) Modular security compliance client, providing on-demand profile-based auditing, alerting, and reporting. Originally designed for Adobe. (linux, windows, corp)
Infection Monkey - (Repo, Home, Docs) Web-based tool for testing a datacenter's resiliency to perimeter breaches and internal server infection. (server)
King Phisher - (Repo, Docs) Server-based phishing campaign toolkit, used to simulate real-world phishing attacks, with GTK-powered client application. (linux, windows, server)
LinOTP - (Repo, Home, WP, Docs) Server supporting two-factor authentication with one-time passwords from several sources, from Yubikeys to SMS. (server)
Maltrail - (Repo) Malicious traffic detection system with web-based monitoring. (linux, server)
MITMproxy - (Repo, Home) Interactive TLS-capable intercepting HTTP proxy for penetration testers and software developers. (linux, windows, mac)
MozDef - (Repo, Docs) Security incident automation with metrics and collaboration tools for defenders. (server)
OpenSnitch - (Repo, Fund) GNU/Linux port of the Little Snitch application firewall. (linux, qt5)
Passit - (Repo, Home, Docs) Password management server, providing storage services and group access control list features. (server)
privacyIDEA - (Repo, Home, WP, Docs) A multi factor authentication server running on premises, supporting many different token types and allowing authentication via REST API, RADIUS, PAM, Windows Credential Provider, SAML, OpenID Connect. (server)
Psono - (Repo, Home, Demo, Docs) Server-based password manager, built for teams. (productivity, server)
Pupy - (Repo, Docs) Remote administration tool and post-exploitation framework, supporting Windows, Linux, Mac OS X, and Android targets. (linux, docker, server)
PyEW - (Repo, Docs) Malware analysis tool, with support for hexadecimal viewing, disassembly, PE and ELF formats, plugins, and more. (console)
RDPY - (Repo) An implementation of the Microsoft Remote Desktop Protocol built on Twisted, including applications for client use, MITM proxy, and Honeypot server. (ops, linux, windows, server)
Recon-ng - (Repo, Home, Docs) Recon-ng is a full-featured reconnaissance framework providing a powerful environment to conduct open source web-based reconnaissance quickly and thoroughly. (linux)
Searx - (Repo, Docs) Self-hosted metasearch engine, aggregating results from more than 70 services while avoiding tracking and profiling. (internet, server, flask)
SpaceSiren - (Repo, Docs) Honeypot management and alert system for AWS tokens, with a fully serverless architecture. (ops, server)
Spiderfoot - (Repo, Home, Docs) Reconnaissance tool that automatically queries over 100 public data sources to gather intelligence on IP addresses, domain names, e-mail addresses, names, and more. (linux, windows, mac, docker, server)
sqlmap - (Repo, Home, PyPI, Docs) Automatic SQL injection and database takeover. (storage, console)
sshuttle - (Repo, Docs) Transparent network proxy server that uses SSH to achieve VPN-like results, without requiring root access. (linux, mac)
Thug - (Repo, Fund, PyPI, Docs) Low-interaction honeyclient designed to mimic the behavior of a web browser in order to detect and emulate malicious contents. (linux, mac)
Universal Radio Hacker (URH) - (Repo) Wireless protocol investigator, with a focus on analyzing proprietary IoT communication. (linux, windows, mac)
XSStrike - (Repo) Cross Site Scripting (XSS) detection suite equipped with multiple hand-written parsers, a payload generator, a fuzzing engine, and a performance-focused crawler. (console)

Docs

asciidoc - (Repo) Text document format for writing notes, documentation, articles, books, slideshows, man pages & blogs. (console)
doc2dash - (Repo, Home, PyPI) Extensible CLI-based Documentation Set generator intended for use with Dash.app and other compatible API browsers. (linux, mac)
Gaphor - (Repo, Docs) Simple UML modeling tool designed for beginners. (graphics, linux, windows, mac, flatpak, gtk)
Kuma - (Repo, Home, Docs) The platform powering the Mozilla Developer Network (MDN) (server, django)
mkdocs - (Repo, Home, PyPI) Simple, customizable project documentation, with built-in dev server. (console)
readthedocs.org - (Repo, Home, Docs) Continuous integration platform for building and hosting documentation. (server, django)
Sphinx - (Repo, Home, PyPI) Documentation tool for interconnected bodies of authorship, from code documentation to books. Used by the official Python docs, and many other projects (not all of them Python). (console)

Editor

Algojammer - (Repo, Demo) An experimental, proof-of-concept IDE to assist with algorithm-writing in a competition setting. (linux, windows, mac, tk)
Black - (Repo, PyPI, Docs) Uncompromising automatic formatter for Python code. (console)
Eric IDE - (Repo, Home) Python editor and IDE, based on Qt, integrating Scintilla editor control. (linux, windows, mac, qt5)
Gedit - (Repo, WP) The default GNOME text editor makes extensive use of Python, in addition to C. (linux, c, gtk)
Jupyter Notebook - (Repo, Home, WP) Web-based, extensible notebook environment for interactive computing. (linux, windows, mac)
Komodo Edit - (Repo, Home, WP) Multi-language code editor, written in JS, Python, and C++, based on the Mozilla platform. (linux, windows, mac, cpp, js)
Leo Editor - (Repo, Home, WP) Personal Information Manager (PIM), IDE, and outliner with a holistic approach to programming and writing. (linux, windows, mac, qt5)
mu - (Repo, Home) A small, simple editor designed for beginner Python programmers. (linux, windows, mac, qt5)
Ninja IDE - (Repo, Home, WP) Cross-platform Python IDE with project management, linting, extensions, and more. (linux, windows, mac, qt5)
Pluma - (Repo) Small and lightweight UTF-8 text editor for the MATE environment. Based on gedit. (linux, c, gtk)
ReText - (Repo, PyPI, Docs) Simple but powerful editor for Markdown and reStructuredText markup languages. (linux)
Spyder IDE - (Repo, Home, WP) Scientific editing and execution environment designed by and for scientists, engineers, and data analysts using Python. (linux, windows, mac, qt5)
Thonny - (Repo, Home, WP) Cross-platform Python IDE for beginners, designed for learning to code. (linux, windows, mac, tk)

Package Managers

Conan - (Repo, Home, Docs) Decentralized package manager for binary package management, targeted at C/C++ developers. (linux, windows, mac)
Conda - (Repo, Home, WP) OS-agnostic, system-level binary package manager and ecosystem, with a focus on Python and high-performance scientific computing. (linux, windows, mac, corp)
dnf - (Repo, WP, Docs) Dandified YUM (DNF) is the successor to yum and works everywhere yum worked. (linux, corp)
pip - (Repo, Home, WP, PyPI) Python's go-to package manager, with a wide range of features and platform support. (linux, windows, mac)
pip-tools - (Repo) A set of command line tools to help you keep your pip-based packages fresh, even when you've pinned them. (linux, windows, mac)
pipenv - (Repo, Docs) Wrapper around pip, virtualenv, and pip-tools for a more holistic package management workflow. (linux, windows, mac)
Poetry - (Repo, Home, Docs) An independent approach to Python dependency management and packaging. (linux, windows, mac)
Portage - (Repo, WP) Platform-agnostic Package management system created for and used by Gentoo Linux and also by Chrome OS, Sabayon, and Funtoo Linux. Inspired by FreeBSD ports. (linux)
Solaris IPS - (Repo) Software delivery system backed by network repository, featuring safe execution for zones, use of ZFS for efficiency and rollback, preventing the introduction of invalid packages, and efficient use of bandwidth. (linux, corp)
Spack - (Repo, Home, Docs) Language-independent package manager for supercomputers, Mac, and Linux, designed for scientific computing. (science, linux, mac)
yum - (Repo, Home, WP) Automatic updater and package installer/remover for RPM-based systems (Fedora, RHEL, etc.). (linux, corp)

Package Repositories

Bandersnatch - (Repo) PyPI mirror client complying with PEP 381. (server, corp)
devpi - (Repo, Docs) PyPI staging server, as well as a packaging, testing, release tool, complete with web and search interface. Like a local PyPI. (server)
distro-tracker - (Repo, Demo, Docs) Web application designed to follow the evolution of a Debian-based distribution with email updates and a comprehensive web interface. Powers the Debian Package Tracker. (server)
SweetTooth Web - (Repo, Home) The web store for extensions to the GNOME desktop environment, supporting adding and updating extensions directly from the browser. (server)
Warehouse - (Repo, Fund, Docs) Server software that powers PyPI, where most Python libraries are downloaded from. (server, fnd)

Build

bitbake - (Repo, WP, Docs) Generic task execution engine that allows shell and Python tasks to be run efficiently and in parallel while working within complex inter-task dependency constraints. (linux)
buildbot - (Repo, WP, Docs) Job scheduling system tailored to the needs of continuous integration and software packaging. (server)
Buildout - (Repo, WP, Docs) Extensible deployment automation tool designed for application-centric assembly and deployment, as well as repeatable Python software builds. (linux, windows, mac)
doit - (Repo, Home, Fund, Docs) Command-line task management and automation tool, with directives written in Python. (linux, windows, mac)
GYP - (Repo, Home, WP) AKA 'Generate Your Projects', a build system that generates other build systems. (linux, windows, mac)
JHBuild - (Repo, Home, gh, Docs) Tool designed to ease building collections of packages, originally written to build the GNOME desktop from sources. (linux)
Meson - (Repo, Home) Build system designed for speed and user-friendliness. (linux, windows, mac)
Pants - (Repo, Home) Build system designed for monolithic repositories. (linux, mac, corp)
PlatformIO Core - (Repo, Home, Fund, PyPI, Docs) Multiplatform CLI build system and library manager for IoT development. (linux, windows, mac)
redo - (Repo, PyPI, Docs) A recursive, general-purpose build sytem, replacing make with original design by DJB. (linux, windows, mac, console)
SCons - (Repo, Home, WP) Domain-specific language and build tool, designed to replace Make, autoconf, and ccache. (linux, windows, mac)
Snapcraft - (Repo, Home, Docs) A command-line tool to package, distribute, and update apps for Linux and IoT using containerization, developed by Canonical. (linux)
Waf - (Repo, Home, WP, Docs) Cross-platform build system designed to improve on SCons. (linux)

Shell

Ergonomica - (Repo, Docs) Cross-platform shell language based on S-expressions combined with traditional shell features. (linux, windows, mac)
Oil - (Repo, Home) A new bash- and dash backwards-compatible shell, with an improved language of its own. (linux)
Xonsh - (Repo, Home) Cross-platform shell language and command prompt. The language is a superset of Python 3.4+ with additional shell primitives. (linux, windows, mac)

Other Dev projects

asciinema - (Repo, Home) Terminal session recorder and replayer. (linux, mac)
autojump - (Repo) A cd with many heuristics to speed up console filesystem navigation. (console)
coala - (Repo, Home, PyPI) Unified command-line interface for linting and fixing code, regardless of programming language. (console)
Cookiecutter - (Repo, PyPI, Docs) Utility for creating new projects from shareable templates. (console)
Cython - (Repo, Home, PyPI, Docs) Language and compiler designed for high-performance Python and C interoperability. (linux, windows, mac)
detect-secrets - (Repo) An enterprise-friendly CLI for auditing, detecting, and preventing secrets in code. (security, linux, windows, mac)
Docker Compose - (Repo, Docs) Docker Compose is a tool for defining and running multi-container Docker applications. (linux, windows, mac, corp)
doitlive - (Repo, PyPI, Docs) Tool for live presentations in the terminal. (linux, mac)
DrawBot - (Repo, Home, WP) A powerful programmatic 2D drawing application for MacOS X which generates graphics from Python scripts. (graphics, education, mac)
gdbgui - (Repo, Home, PyPI) Browser-based frontend for gdb. (linux, windows, mac)
GNS3 GUI - (Repo, Home, PyPI, Docs) Graphical Network Simulator used to emulate, configure, test and troubleshoot virtual and real networks. (Backed by server component here.) (linux, windows, mac)
howdoi - (Repo, PyPI) Instant coding answers from StackOverflow on your command line. (console)
httpie - (Repo, Home, PyPI) Command-line HTTP client with JSON support, syntax highlighting, wget-like downloads, extensions, and more. (internet, linux, windows, mac)
IPython - (Repo, PyPI, Docs) Set of enhancements to Python, wrapping it for richer interactivity. (console)
LocalStack - (Repo, Home, PyPI) Self-hostable version of many AWS services, including S3, Route53, Lambda, Redshift, and much more, designed for testing cloud-centric code. (server)
Locust - (Repo, Home, Docs) Scalable user load testing tool for web sites, featuring an interactive web interface. (server)
MLflow - (Repo, Home, Docs) Integrated command-line application and web service, supporting an end-to-end machine-learning workflow around tracking, packaging, and deploying. Developed by Databricks. (organization, linux, mac, corp)
PathPicker - (Repo, Home) Shell utility to interactively select paths from the output of other commands. (linux, mac)
PeachPy - (Repo) Highly portable assembler with unified syntax, sporting an extensive user list, including many cryptography libraries for Go. (linux, windows)
PINCE - (Repo) Debugging frontend for GDB focused on reverse engineering video games. (linux, qt5)
Plinth - (Repo, Home, Docs) The core functionality and web front-end of FreedomBox, an easy-to-manage, privacy-oriented home server. (linux, server)
Polyaxon - (Repo, Home, Docs) A web-based platform for reproducible and scalable machine learning experiment management and metrics-tracking, based on kubernetes, with support for TensorFlow, PyTorch, Keras, and many more. (server)
PPCI - (Repo, Demo, gh, PyPI, Docs) The Pure Python Compiler Infrastructure is a compiler written entirely in Python, containing front-ends for various programming languages (C, c3, WebAssembly, and others) as well as machine code generation backends for various CPUs (6500, arm, avr, x86_64, openrisc, among others). (linux, windows, mac)
pre-commit - (Repo, Home, PyPI) A framework for managing and maintaining multi-language git hooks. (linux, windows, mac)
RedHat Anaconda - (Repo, Docs) Installation program used by Fedora, Red Hat Enterprise Linux, and other Linux distributions. (linux, gtk)
Robot Framework - (Repo, Home, PyPI) Generic, cross-platform, and language-independent automation framework for acceptance testing, acceptance test driven development (ATDD), and robotic process automation (RPA). Extensible in Python and Java. (console)
ScratchABit - (Repo) Easily retargetable and hackable interactive disassembler with IDAPython-compatible plugin API. (linux, tui)
Script Server - (Repo, Demo, Docs) Turn scripts into interactive, validated, authenticated, auditable web UIs, without modifying the scripts. (server)
Sentry - (Repo, Home) Web service and frontend for cross-platform application monitoring, with a focus on error reporting. (server, corp, django)
Socorro - (Repo, Docs) Web service for collecting crash statistics from Mozilla products, including Firefox, Thunderbird, and others. (server)
Taiga - (Repo, Home, Docs) Web application built for managing projects with agile development processes. (organization, server, django)
Thumbor - (Repo, Home, Docs) Photo thumbnail service with resizing, flipping, and smart cropping of images. (graphics, server)
Ubiquity - (Repo, WP) The default installer for Ubuntu and its derivatives, designed to be run from Live CD or USB. (linux, gtk, qt)
Voltron - (Repo) Extensible debugger wrapper aiming to improve the user experience of various debuggers, such as LLDB, GDB, and WinDbg. (linux, windows, mac)
YunoHost - (Repo, Home, Docs) Server operating system based on Debian Linux aiming to make self-hosting accessible to as many people as possible, with support for several types of hardware. (linux, server)

Misc

CourtListener - (Repo, Home, WP) Web application which provides a graph-based search interface and API with 900,000 minutes of oral argument recordings, more than eight thousand judges, and more than three million opinions. Also powers RECAP search. (server)
Guake - (Repo, Home, PyPI) Drop-down terminal for GNOME, reminiscent of first-person game command consoles. (linux, gtk)
Home Assistant - (Repo, Home, Demo, Docs) Home automation platform that puts local control and privacy first. (linux)
JARVIS on Messenger - (Repo, Home) Facebook Messenger bot with a wide assortment of features. (server)
NFO Viewer - (Repo, Home) A simple viewer for NFO files and the ASCII art therein, with preset fonts, encodings, automatic window sizing, and clickable hyperlinks. (graphics, linux, windows)
Nicotine+ - (Repo) Graphical desktop client for the Soulseek peer-to-peer system. (linux, windows, gtk)
Nimbus - (Repo, Home) Infrastructure-as-a-Service platform geared toward scientific cloud computing. (linux)
OpenLP - (Repo, Home) Presentation software geared toward church usage. (linux, windows, mac, qt5)
qtile - (Repo, Home) A small, flexible, scriptable tiling window manager. (linux)
uMap - (Repo, Docs) Web application allowing users to create maps with OpenStreetMap layers and embed it on other sites. (server)
Wammu - (Repo, Home) GUI phone manager with read/write support for contacts, todo, calendar, SMS, and more, primarily designed for Nokia and AT-compatible phones. (linux, windows)
Wicd - (Repo, Home, WP) Graphical utility for managing wired and wireless connections on Linux. (linux, gtk)
Xpra - (Repo, Home) Cross-platform remote display server and client for forwarding applications and desktop screens. (linux, windows)

Conclusion

If you have a project to add, please let us know!