Discover lh3/lianti Open Source project by Heng Li (@lh3)

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Rank 1,016,462 (Top 21 %)
Language
C
Created over 7 years ago
Updated over 5 years ago

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Tools to process LIANTI sequence data

minimap2

A versatile pairwise aligner for genomic and spliced nucleotide sequences

1,754

bwa

Burrow-Wheeler Aligner for short-read alignment (see minimap2 for long-read alignment)

1,504

seqtk

Toolkit for processing sequences in FASTA/Q formats

1,363

bioawk

BWK awk modified for biological data

590

minigraph

Sequence-to-graph mapper and graph generator

402

miniprot

Align proteins to genomes with splicing and frameshift

316

miniasm

Ultrafast de novo assembly for long noisy reads (though having no consensus step)

wgsim

gfatools

Tools for manipulating sequence graphs in the GFA and rGFA formats

208

biofast

Benchmarking programming languages/implementations for common tasks in Bioinformatics

175

readfq

Fast multi-line FASTA/Q reader in several programming languages

170

cgranges

A C/C++ library for fast interval overlap queries (with a "bedtools coverage" example)

165

kmer-cnt

Code examples of fast and simple k-mer counters for tutorial purposes

C++

162

pangene

Constructing a pangenome gene graph

158

psmc

Implementation of the Pairwise Sequentially Markovian Coalescent (PSMC) model

147

bedtk

A simple toolset for BED files (warning: CLI may change before bedtk becomes stable)

134

ksw2

Global alignment and alignment extension

127

yak

Yet another k-mer analyzer

111

fermikit

De novo assembly based variant calling pipeline for Illumina short reads

TeX

108

minimap

This repo is DEPRECATED. Please use minimap2, the successor of minimap.

106

hickit

TAD calling, phase imputation, 3D modeling and more for diploid single-cell Hi-C (Dip-C) and general Hi-C

105

bgt

Flexible genotype query among 30,000+ samples whole-genome

dipcall

Reference-based variant calling pipeline for a pair of phased haplotype assemblies

JavaScript

srf

SRF: Satellite Repeat Finder

TeX

unimap

A EXPERIMENTAL fork of minimap2 optimized for assembly-to-reference alignment

minipileup

Simple pileup-based variant caller

fermi

A WGS de novo assembler based on the FMD-index for large genomes

dna-nn

Model and predict short DNA sequence features with neural networks

fermi-lite

Standalone C library for assembling Illumina short reads in small regions

bfc

High-performance error correction for Illumina resequencing data

TeX

ropebwt2

Incremental construction of FM-index for DNA sequences

TeX

tabtk

Toolkit for processing TAB-delimited format

gwfa

Proof-of-concept implementation of GWFA for sequence-to-graph alignment

CHM-eval

TeX

miniwfa

A reimplementation of the WaveFront Alignment algorithm at low memory

jstreeview

Interactive phylogenetic tree viewer/editor

JavaScript

samtools

This is *NOT* the official repository of samtools.

etrf

Exact Tandem Repeat Finder (not a TRF replacement)

ref-gen

Human reference genome analysis sets

Makefile

bioseq-js

For live demo, see http://lh3lh3.users.sourceforge.net/bioseq.shtml

HTML

lv89

C implementation of the Landau-Vishkin algorithm

C++

partig

An experimental tool to estimate the similarity between all pairs of contigs

asub

A unified array job submitter for LSF, SGE/UGE and Slurm

Perl

klib.nim

Experimental getopt, gzip reader, FASTA/Q parser and interval queries in nim-lang

Nim

calN50

Compute N50/NG50 and auN/auNG

JavaScript

sdust

Symmetric DUST for finding low-complexity regions in DNA sequences

gffio

pre-pe

Preprocessing paired-end reads produced with experiment-specific protocols

hapdip

The CHM1-NA12878 benchmark for single-sample SNP/INDEL calling from WGS Illumina data

JavaScript

fermi2

misc

Useful small programs

varcmp

The first CHM1 paper (Li, 2014)

TeX

minisv

Lightweight mosaic/somatic SV caller for long reads (WIP)

JavaScript

rtgeval

Wrapper for RTG's vcfeval; DEPRECATED!

Shell

nasw

Dynamic programming for aa-to-nt alignment with affine gap, splicing and frameshift

sgdp-fermi

FermiKit small variant calls for public SGDP samples

gfa1

This repo is deprecated. Please use gfatools instead.

pubLRasm

PortableCrystal

Portable Crystal binary distributions for Linux on x86_64

foreign

Modified or extracted from other programs

trimadap

Fast but inaccurate adapter trimmer for Illumina reads

lh3-snippets

ropebwt3

Construction and utility of BWT for DNA string sets

treebest

TreeBeST: Tree Building guided by Species Tree

unicall

A wrapper for calling small variants from human germline high-coverage single-sample Illumina data

Perl

fastARG

Fast heuristic ARG construction

proot-wrapper

Demonstrating the PRoot program

Perl

rmaxcut

An experimental tool to find approximate max-cuts in a large graph

bwa-docker

Minimal docker image for bwa. Not developed any more.

sdg

EXPERIMENTAL implementation of side graph

naivepca

Naive PCA for genotype data

mdust

mdust from DFCI Gene Indices Software Tools (archived for a historical record only)

editdist-U85

Fast implementation of Ukkenon's O(ND) algorithm for computing edit distance

lh3.github.com

TeX

libdivsufsort

Automatically exported from code.google.com/p/libdivsufsort

mem-paper

Manuscript for BWA-MEM

bcf2

Experimental bcftools port to support BCF2; DEPRECATED by htslib and htsbox

thesis

PhD thesis

TeX

ropebwt

fermi-paper

The first fermi paper (Li, 2012)

crlf

Concise Run-Length Format for small alphabets; DEPRECATED

psnw

prototype

centos5-vm

Instructions on how to deploy CentOS 5 virtual machines

mag2gfa

DEPRECATED. Code has been moved to lh3/gfa1/misc

ibsget

Download files from Illumina BaseSpace (*OUTDATED* as BaseSpace has changed APIs)

smtl-paper

Samtools statistics paper (Li, 2011)

Lua

mssa-bench

Evaluating the performance of multi-string SA construction

samtools-legacy

For testing only. DON'T USE!

lh3/lianti

lh3

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