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  • Created 10 months ago
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Repository Details

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1

Suite

Open Systems Pharmacology Suite Setup
Rich Text Format
99
star
2

PK-Sim

PK-Sim® is a comprehensive software tool for whole-body physiologically based pharmacokinetic modeling
C#
89
star
3

Forum

Discussion forum for the Open Systems Pharmacology Project
61
star
4

OSPSuite-R

R package for the OSPSuite
R
28
star
5

MoBi

MoBi® is a software tool for multiscale physiological modeling and simulation
C#
25
star
6

Glucose-Insulin-Model

The physiologically-based whole-body model of the glucose-insulin-glucagon regulatory system
MATLAB
19
star
7

OSP-based-publications-and-content

Publications of all kind based on the Open Systems Pharmacology Suite
15
star
8

OSP-PBPK-Model-Library

Library of released PBPK substance models and evaluation reports
MATLAB
10
star
9

TLF-Library

TLF Library implementation in R
R
9
star
10

docs

Open Systems Pharmacology - Live Documentation
HTML
9
star
11

Pregnancy-Models

Physiologically Based Pharmacokinetic Models for Pregnant Women
6
star
12

OSPSuite.ReportingEngine

R implementation of the reporting engine
R
5
star
13

Digoxin-Model

Whole-body PBPK model of digoxin as P-gp DDI victim drug
R
4
star
14

OSPSuite.Core

Core functionalities of the Open Systems Pharmacology Suite
C#
4
star
15

Inhalation-model

Implementation of inhalation model in MoBi
R
4
star
16

OSPSuite.Documentation

Documentation files for the Open Systems Pharmacology Suite
4
star
17

Skin-permeation-model

Implementation of Dancik et al (2013) skin permeation model in MoBi
4
star
18

OSPSuite.SimModel

Calculation engine for models built with PK-Sim® or MoBi®
C++
4
star
19

R-Toolbox

R
3
star
20

Vancomycin-Model

Whole-body PBPK model of Vancomycin
MATLAB
3
star
21

ISSX-2017-Cologne

Training materials for the OSP workshop at ISSX 2017, Cologne
3
star
22

BERLIN-2019-WORKSHOP

[FULLY BOOKED] SGS Exprimo and the FU Berlin will run a two-days hands-on PK-Sim® & MoBi® workshop on introducing PBPK for human dose projection and drug-drug interaction (DDI) prediction on 21st-22nd Feb 2019 at the Institute of Pharmacy, FU-Berlin, Germany.
3
star
23

OSPSuite.ParameterIdentification

R package for parameter identification for OSPS models
R
3
star
24

Matlab-Toolbox

Collection of Matlab® functions for the processing of PK-Sim® or MoBi® models
Rich Text Format
2
star
25

Vision-Mission

Vision & Mission of Open Systems Pharmacology
2
star
26

PAGE2017-Budapest

Training materials for the OSP workshop at PAGE 2017 Budapest
2
star
27

OSP-Qualification-Reports

Qualification Reports recreated with every new OSP Release
2
star
28

FDA-OSP-workshop-April-2021

2
star
29

OSPSuite.DataBinding

DataBinding framework for WinForms application used in the Open Systems Pharmacology Suite
C#
2
star
30

OSPSuite.Plots

Figures and dependent tables which are used by R packages in the Open Systems Pharmacology ecosystem
R
2
star
31

ACoP-2018-Workshop

PK-Sim® & MoBi® (OSPS®) workshop on integrating PBPK with QSP
2
star
32

Thyroid-Hormones-PB-QSP-Model

Physiology-based systems pharmacology model of thyroid hormones regulation in rat and human
R
2
star
33

DCI

Data Component Interface used in the Open-Systems-Pharmacology Suite
C++
1
star
34

AGePOP-OSP-Workshop-2021

1
star
35

PAGE-2019-PBPK-Workshop

PK-Sim® & MoBi® (OSP Suite) workshop on PBPK
1
star
36

BOSTON-2018-Workshop

PK-Sim® & MoBi® workshop on integrating PBPK with QSP
1
star
37

Lung-absorption-model

Pulmonary drug absorption implemented in MoBi (Eriksson et al. 2020)
1
star
38

Clarithromycin-Midazolam-DDI

Modeling of published clinical Clarithromycin-Midazolam-DDI studies for model evaluation
1
star
39

InstallationValidator

Installation Validation Tool for the Open Systems Pharmacology Suite
C#
1
star
40

Metoprolol-Model

PBPK model of metoprolol and metoprolol-CYP2D6 drug-gene interactions
1
star
41

PharMetrX-Workshop-March-2018

Training materials for the PharMetrX POSP PBPK workshop, Potsdam March 2018
1
star
42

Reporting-Engine

(Matlab) Reporting-Engine
MATLAB
1
star
43

Theophylline-Model

Whole-body PBPK model of theophylline as CYP1A2 DDI victim drug
1
star
44

Quinidine-DDGI-Model

1
star
45

Pediatric_Qualification_Package_CYP2C8_Ontogeny

Pediatric Qualification Package for CYP2C8 Ontogeny
MATLAB
1
star
46

Erythromycin-Felodipine-DDI

1
star
47

Carbamazepine-Alprazolam-DDI

Modeling of published clinical Carbamazepine-Alprazolam-DDI studies for model evaluation
1
star
48

Ritonavir-Model

PBPK model for ritonavir
R
1
star
49

Clarithromycin-Sildenafil-DDI

1
star
50

Carbamazepine-Midazolam-DDI

Modeling of published clinical Carbamazepine-Midazolam-DDI studies for model evaluation
1
star
51

Carbamazepine-Efavirenz-DDI

Modeling of published clinical Carbamazepine-Efavirenz DDI studies for model evaluation
1
star
52

Erythromycin-Sildenafil-DDI

1
star
53

Itraconazole-Sildenafil-DDI

1
star
54

Erythromycin-Carbamazepine-DDI

Modeling of published clinical Erythromycin-Carbamazepine DDI studies for model evaluation
1
star
55

ACoP-2017-FortLauderdale

Training materials for the OSP workshop at ACoP 2017, Fort Lauderdale
1
star
56

Levonorgestrel

Whole-body PBPK model of levonorgestrel with and without ethinyl estradiol as CYP3A4 DDI victim drug
1
star
57

Voriconazole-Model

Whole-body PBPK model of voriconazole as CYP2C19 substrate and CYP3A4 perpetrator drug
1
star
58

Quinidine-Model

1
star
59

OSPSuite.DataBinding.DevExpress

DataBinding Framework for DevExpress components used by the Open Systems Pharmacology Suite
C#
1
star
60

BE-Studies

1
star
61

ASCPT-Satelite-OSPS-Workshops

ASCPT2020 satellite workshops: PK-Sim® & MoBi® hands-on training for PBPK and PBPK-based QSP at University of Houston, College of Pharmacy (www.esqlabs.com/news-events)
1
star
62

Gene-Expression-Databases

R
1
star
63

Cimetidine-Alfentanil-DDI

Modeling of published clinical Cimetidine-Alfentanil-DDI studies for model evaluation
1
star
64

Cimetidine-Verapamil-DDI

Modeling of published clinical Cimetidine-Verapamil-DDI studies for model evaluation
1
star
65

Itraconazole-Model

Whole-body PBPK model of itraconazole as CYP3A4 and P-gp DDI perpetrator drug
MATLAB
1
star
66

Cimetidine-Midazolam-DDI

Modeling of published clinical Cimetidine-Midazolam-DDI studies for model evaluation
1
star
67

Cimetidine-Alprazolam-DDI

Modeling of published clinical Cimetidine-Alprazolam-DDI studies for model evaluation
1
star
68

Cimetidine-Carbamazepine-DDI

Modeling of published clinical Cimetidine-Carbamazepine DDI studies for model evaluation
1
star
69

Cimetidine-Model

Whole-body PBPK model of cimetidine (OCT2/MATE and CYP3A4 DDI perpetrator drug)
MATLAB
1
star
70

Cimetidine-Triazolam-DDI

Modeling of published clinical Cimetidine-Triazolam-DDI studies for model evaluation
1
star
71

OSPSuite.RUtils

Utility functions for Open Systems Pharmacology R packages
R
1
star