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Repository Details

More Repositories

1

TwoSampleMR

R package for performing 2-sample MR using MR-Base database
R
411
star
2

PHESANT

PHESANT - PHEnome Scan ANalysis Tool (pheWAS, Mendelian randomisation (MR)-pheWAS etc.) in UK Biobank
R
136
star
3

gwasglue

Linking GWAS data to analytical tools in R
R
110
star
4

ieugwasr

R interface to the IEU GWAS database API
R
72
star
5

gwasvcf

Reading, querying and writing GWAS summary data in VCF format
HTML
66
star
6

awesome-ai

Awesome list for all things AI, ML and deep learning
51
star
7

gwas2vcf

Convert GWAS summary statistics to VCF
Python
47
star
8

MRInstruments

Data objects for various sets of instruments
R
43
star
9

epigraphdb-pqtl

This is the github repository to provide the R scripts been used in the phenome-wide Mendelian randomization study of plasma proteome.
R
37
star
10

Health-and-Wellbeing-MR

R
27
star
11

epigraphdb

Examples on using EpiGraphDB
Jupyter Notebook
26
star
12

epigraphdb-r

R package for epigraphdb
R
26
star
13

metaboprep

a pipeline of metabolomics data processing and quality control
R
22
star
14

gwas-vcf-specification

Specification for the GWAS-VCF format (manuscript in preparation)
22
star
15

gwasglue2

Connecting GWAS summary data to analytical tools
R
17
star
16

PhenoSpD

R
17
star
17

MELODI-Presto

A fast and programmatic MELODI
Jupyter Notebook
15
star
18

UKBiobankGWAS

Notes and code for running UK Biobank GWAS at the MRC IEU
Python
14
star
19

godmc

GoDMC analysis pipeline
R
13
star
20

PHESANT-MR-pheWAS-BMI

R
11
star
21

GLU

A tool for analysing continuous glucose monitoring (CGM) data in epidemiology.
R
10
star
22

ieugwaspy

Python interface to the MRC IEU GWAS database API
Python
9
star
23

GeneHackman

Pipeline for genetic epidemiology projects at Univsersity of Bristol
R
9
star
24

genetics.binaRies

Binaries for tools used in genetics in an R package
R
9
star
25

vectology

Using language models and ontology topology to perform semantic mapping of traits between biomedical datasets
Jupyter Notebook
9
star
26

CheckSumStats

R
8
star
27

BiobankPhenotypes

Python
8
star
28

pygwasvcf

Python library for reading GWAS summary statistics in GWAS-VCF files
Python
7
star
29

melodi

Mining Enriched Literature Objects to Derive Intermediates
HTML
7
star
30

ariesmqtl

Scripts to run mQTL analyses as described in the ARIES mQTL paper
Python
7
star
31

bp-drug-mr

Multi-ancestry MR of blood pressure drug targets
HTML
6
star
32

temmpo

Text mining for mechanism prioritisation
Python
6
star
33

godmc_phase2_analysis

HTML
6
star
34

qqman_multiple_colours

Manhattan plot function which highlights SNPs in different colours
R
6
star
35

UKBActivityBoutLength

Assessing association of physical activity types and bout length in UK Biobank
R
6
star
36

mrbase_casestudies

Using the MR-Base platform to investigate risk factors and drug targets for thousands of phenotypes
HTML
6
star
37

introduction-to-r

HTML
5
star
38

opengwas-api

API for MRC-IEU OpenGWAS platform (https://gwas.mrcieu.ac.uk)
Python
5
star
39

epigenetics-journal-club

Repository for the IEU epigenetics journal club papers, presentations and scripts
Python
5
star
40

Lifecourse-GWAS

R
5
star
41

genetic-epidemiology-practicals

Practicals for Genetic epidemiology short course
R
5
star
42

ukbb-prot-prs

R
5
star
43

gwas-vcf-performance

Comparison between VCF and plain text storage formats for GWAS summary statistics
HTML
4
star
44

MR-maternal-smoking

Analysis code for proxy gene-by-environment Mendelian randomization of maternal smoking on offspring health
R
4
star
45

MR-randomization-test

R
4
star
46

Psychiatric-disorder-pheWAS-UKBB

R
4
star
47

ewascatalog-r

R
4
star
48

varGWAS

GWAS of trait variance (C++)
R
3
star
49

Smoking_IBD

Scripts for analysing the association between smoking and inflammatory bowel disease (IBD)
R
3
star
50

epigraphdb-ctda

codes for the epigraphdb CTAD database
R
3
star
51

education_mentalhealth_CVD

R
3
star
52

GwasDataImport

R package to upload data to GWAS database
R
3
star
53

biorxiv-medrxiv-tdm

Jupyter Notebook
3
star
54

ewascatalog

HTML
3
star
55

PHESANT-MR-PheWAS-Insomnia

An MR-PheWAS of insomnia using UK Biobank and PHESANT.
R
3
star
56

mendelvar_standalone

Standalone version of the MendelVar pipeline
Python
3
star
57

mrcieu.r-universe.dev

R packages for mrcieu.r-universe.dev
3
star
58

sleep_duration_pregnancy

Here we provide scripts used in 'Investigating causal relations between sleep duration and risks of adverse pregnancy and perinatal outcomes: Linear and nonlinear Mendelian randomization analyses in up to 356,069 European women'
R
3
star
59

opengwas-requests

A place to request or contribute data to the IEU GWAS database
3
star
60

hie-ml

R
2
star
61

vitD_bonehealth

ALSPAC vitamin D and bone health MR study
R
2
star
62

PHESANT-MR-pheWAS-smoking

MR-pheWAS of smoking heaviness
R
2
star
63

met-d-import

UKBB Nightingale import to OpenGWAS
R
2
star
64

queryukbppp

Query UKB-PPP data
R
2
star
65

Schizophrenia_Fertility_Paper

Stata
2
star
66

handedness-ewas

R
2
star
67

epigraphdb_web

Web application (web UI) of the EpiGraphDB platform
Vue
2
star
68

gwas_processing

Python
2
star
69

IGD-elasticsearch

Docker container for creating indexes and indexing GWAS data
Python
2
star
70

variance-iv4-violation

R
2
star
71

varGWAS-ukbb-biomarkers

R
2
star
72

vcf-reference-datasets

Shell
2
star
73

MR-PREG

Repository for the MR-PREG collaboration
R
2
star
74

PHESANT-IV-pheWAS-relative-school-age

IV-pheWAS of relative school age
R
1
star
75

opengwas-infpval-fix

Documentation and fixes for p-value issues for some datasets
Python
1
star
76

godmc_phase1_analysis

Shell
1
star
77

varGWASR

R package to perform regression-based Brown-Forsythe test
R
1
star
78

activityBigrams

Physical activity phenotyping with activity bigrams, and their association with BMI
MATLAB
1
star
79

COVIDITY_selbias

COVIDITY BHF-Project - Working Package 3 about selection bias in COVID-19 studies across UK cohorts
R
1
star
80

met-e-import

R
1
star
81

prot-c-import

Import Suhre et al 2017 protein data
R
1
star
82

opengwas

1
star
83

bbj-a-import

Import Japan Biobank GWAS
R
1
star
84

epigraphdb-asq

Annotated Semantic Queries
Jupyter Notebook
1
star
85

mrtwin_power

R
1
star
86

cistrans_pqtl

R
1
star
87

finn-a-import

FinnGen R2 GWAS data import
R
1
star
88

MVMRalcsmo

A repository of code for a MVMR study of the effect of alcohol and smoking on lung function
R
1
star
89

IlluminaFinalRep_LRRBAF

Estimate LRR and BAF from Illumina Final Report
Python
1
star
90

prot-lungcancer

Protein associations with lung cancer pre
R
1
star
91

opengwas-reports

Report module for IEU GWAS pipeline
R
1
star
92

aries

Functions for loading the ARIES DNA methhylation data
HTML
1
star
93

upptime

Use upptime to monitor web platform status
JSON
1
star
94

finn-b-import

Import Finngen R5 GWAS
R
1
star
95

panukbb_gwas_import

Import pan UKBB GWAS analysis https://pan.ukbb.broadinstitute.org/
R
1
star
96

gwas2vcfweb

Web interface for gwas2vcf
HTML
1
star
97

mrmn

Website for the Mendelian randomization Methods Network
1
star
98

AFS_AAM_LifeHistory

Analysis scripts for "Using Mendelian randomization to investigate life history theory: the effects of age at menarche and first sexual intercourse on reproductive and behavioural outcomes"
R
1
star
99

oci-elastic

IEU version of https://github.com/cloud-partners/oci-elastic
HCL
1
star
100

mdNLR-and-Rheumatoid-Arthritis-Script

Rheumatoid arthritis (RA) is a disease of chronic systemic inflammation (SI). In the present study, we used four datasets to explore whether methylation-derived neutrophil-to-lymphocyte ratio (mdNLR) might be a marker of SI in new onset, untreated, and treated prevalent RA cases and/or a marker of treatment response to the tumour necrosis factor inhibitor (TNFi) etanercept.
R
1
star