CardiacModelling/ap-nimbus-client

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Created almost 3 years ago
Updated about 2 months ago

CardiacModelling/ap-nimbus-client

CardiacModelling

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markov-builder

Tool for building and manipulating Markov models of ion-channel kinetics

fitting-notebooks

Examples of parameter estimation in cardiac cell electrophysiology using Myokit and PINTS.

Jupyter Notebook

FourWaysOfFitting

Code to compare four different ways to fit an ion current model

RapidCharacterisationProtocols

Collection of experimental protocols in common patch clamp formats for rapid characterisation of ion channels

fickleheart-method-tutorials

Code for the tutorials in the Fickle Heart model calibration with discrepancy 2020 paper.

VoltageClampModel

Code to add a mathematical model of voltage-clamp artefacts to your ion channel simulations

hERGRapidCharacterisation

Rapid characterisation of hERG channel kinetics

BenNevis

"Where is Ben Nevis" presents the landscape of Great Britain as a testbed for optimisation and sampling methods.

hERG-binding-mechanisms

Source code and data for reproducing "The impact of uncertainty in hERG binding mechanism on in silico predictions of drug-induced proarrhythmic risk".

WIRES

Figures and code for examples in WIREs review on calibrating electrophysiology models

ionBench

A benchmarking tool for comparing different parameter optimization algorithms for ion channel models

space-filling-designs

Phase-voltage space filling optimal designs in Matlab

ical-model-review

ap-nimbus

Cardiac modelling in containers

ap-nimbus-app-manager

API for cloudified AP Predict

appredict-docker

Gamma_0

Code associated with a publication on the action potential model parameter representing missing charge

nonlinear-time-dependent-leak

Data and code for reproducing the results in the nonlinear time-dependent leak paper.

pcpostprocess

syncropatch_export

tailored-ipsc-models

Code to reproduce the simulations and figures in "Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology"

L-type-Ca-rundown-experiments

An investigation of rundown in automated patch clamp L-type calcium current

Jupyter Notebook