Open Targets (@opentargets)
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opentargets

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Top repositories

1

genetics-sumstat-harmoniser

Harmonise GWAS summary statistics against a reference VCF
Python
38
star
2

gentropy

Open Targets python framework for post-GWAS analysis
Jupyter Notebook
33
star
3

genetics-gold-standards

GWAS gold standards repository
Python
29
star
4

genetics-finemapping

Fine-mapping pipeline for Open Targets Genetics
Python
25
star
5

OnToma

Map your disease and phenotype terms to the Open Targets platform ontology
Python
19
star
6

genetics-colocalisation

Colocalisation pipeline for Open Targets Genetics
Python
16
star
7

issues

Issue tracker for Open Targets Platform and Open Targets Genetics Portal
12
star
8

genetics-docs

11
star
9

genetics-api

Open Targets Genetics GraphQL API
Scala
11
star
10

genetics-v2d-data

Variant to disease dataset workflows for Open Targets Genetics
Python
10
star
11

genetics-l2g-scoring

Locus-to-gene scoring pipeline
Python
10
star
12

platform-api

GraphQL and Rest API rewrite of the current Open Targets platform API
Scala
9
star
13

json_schema

Open Targets target-disease association schema
Python
9
star
14

genetics-v2g-data

Workflows to generate cis-regulatory datasets used for variant-to-gene (V2G) assignment in Open Targets Genetics
Jupyter Notebook
9
star
15

opentargets.github.io

Open Targets corporate website code using Jekyll
HTML
8
star
16

platform-etl-backend

Scala
8
star
17

stopReasons

Analysis on stop reasons
Python
8
star
18

platform-etl-openfda-faers

Open Targets ETL to process OpenFDA FAERS DB
Scala
8
star
19

genetics-sumstat-data

Workflows for processing summary statistics files for Open Targets Genetics
HTML
8
star
20

mendelian-randomisation

R
7
star
21

genetics-backend

QC, spin VMs, load data into DBs, create LUTs and other fun backend stuff we need to do to spin https://genetics.opentargets.org
Python
6
star
22

evidence_datasource_parsers

script to convert phewascatalog database to JSONs, with ENSGIDs and EFO ids.
Python
6
star
23

genetics-pipe

Scala
6
star
24

platform-input-support

Open Targets Platform input support project.
Python
5
star
25

platform-etl-literature

LIterature coNcept Knowledgebase for OpenTarget
Scala
5
star
26

curation

mappings used by the open targets platform to integrate data sources
Python
4
star
27

standalone-deployment-platform

Standalone local deployment for Open Targets Platform
Shell
4
star
28

ot-ui-apps

Open Targets Platform web applications
JavaScript
4
star
29

genetics-variant-annotation

Workflow to produce variant index annotation for Open Targets Genetics
Python
3
star
30

validator

Python
2
star
31

platform-checks

1
star
32

ot-release-metrics

Collection and visualisation of Open Targets Platform release metrics.
Python
1
star
33

finngen2efo

R
1
star
34

terraform-google-opentargets-platform

Terraform module for Open Targets Platform infrastructure definition
HCL
1
star
35

target_safety_data_pipeline

Python
1
star
36

expression_hierarchy

Utility to convert gxa hierarchy files to JSON
Python
1
star
37

orchestration

Open Targets pipeline orchestration layer
Python
1
star
38

baseline-expression

Code and documentation for baseline expression and specificity data.
Jupyter Notebook
1
star