Explore @WGLab Open Source projects

Wang Genomics Lab (@WGLab)

WGLab

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doc-ANNOVAR

Documentation for the ANNOVAR software

InterVar

A bioinformatics software tool for clinical interpretation of genetic variants by the 2015 ACMG-AMP guideline

dragonstar2019

DeepMod

DeepMod: a deep-learning tool for genomic-scale, strand-sensitive and single-nucleotide based detection of DNA modifications

NanoCaller

Variant calling tool for long-read sequencing data

PennCNV

Copy number vaiation detection from SNP arrays

biocluster

Tutorial on building a computing cluster for bioinformatics

phenolyzer

phenotype-based prioritization of candidate genes for human diseases

Bioformer

Bioformer: an efficient BERT model for biomedical text mining

VirTect

Detection of viruses from RNA-Seq on human samples

CancerVar

Clinical interpretation of somatic mutations in cancer

Phen2Gene

Phenotype driven gene prioritization for HPO

LIQA

Long-read Isoform Quantification and Analysis

EHR-Phenolyzer

A pipeline that takes clinical notes from EHRs and generate phenotype terms, then generate ranked gene list

NanoMod

NanoMod: a computational tool to detect DNA modifications using Nanopore long-read sequencing data

RepeatHMM

a hidden Markov model to infer simple repeats from genome sequences

DeepMod2

DNA 5mC methylation detection from Dorado or Guppy basecalled Oxford Nanopore reads

Jupyter Notebook

SeqMule

Automated human exome/genome variants detection from FASTQ files

LongGF

A computational algorithm and software tool for fast and accurate detection of gene fusion by long-read transcriptome sequencing

LinkedSV

Workshop_Annotation

Course materials for "Variants Annotate and Phenotype Analysis"

GenGen

A set of software tools to facilitate GWAS analysis

DeepRepeat

An accurate repeat detection from Nanopore data using deep learning and image techniques

HadoopCNV

HadoopCNV is a MapReduce-based copy number variation caller for genome sequencing data

lncScore

A python package for the identification of lncRNA from the assembled novel transcripts

GDP

Group lasso based Deep Neural Network for Cancer Prognosis

NanoRepeat

NanoRepeat: fast and accurate analysis of Short Tandem Repeats (STRs) from Oxford Nanopore sequencing data

icages

iCAGES (integrated CAncer GEnome Score) is an effective tool for prioritizing cancer driver genes for a patient

PhenoSV

PhenoSV: Interpretable phenotype-aware model for the prioritization of genes affected by structural variants.

PennCNV2

A software package for detection of copy number alterations from tumor samples

SVGen

Simulator for structural variants in various types of next-generation sequencing data

mutformer

A transformer model to predict pathogenic mutations

Jupyter Notebook

iMEGES

integrated Mental-disorder Genome Score

PhenoGPT

Jupyter Notebook

DELongSeq

UROBORUS

UROBORUS: circular RNA identification from RNA-Seq data

AmpBinner

A barcode demultiplexer for Oxford Nanopore long-read amplicon sequencing data

epilepsy-autism-multiplex-network

Jupyter Notebook

PhenCards

Development of phencards.org web server for one stop shop of phenotype information

PennCNV-Seq

Adaption of the original PennCNV algorithm for whole-genome sequencing data

LongReadSum

uniline

Assembly-based analysis

kgev-neo4j

Jupyter Notebook

QuantitativeGenomics2022

w4CSeq

web server of 4C-Seq data analysis pipeline

NanoBinner

Phen2Gene2

Phen2Gene improved and optimized for pipelines

ASD_terminology

Jupyter Notebook

QuantitativeGenomics2023

Materials for Quantitative Genomics 2023 workshop

ContextSV

An alignment-based, generalized structural variant caller for long-read sequencing/mapping data

QuantitativeGenomics2021

lncScore-Java

Prediction of lncRNA from RNA-Seq data

HTT-SNP-Phasing

icages-server

the iCAGES server running on Ruby on Rails