Explore @DSIMB Open Source projects

PoincareMSA

Detection of the structural, evolutionary and functional relationship between different proteins and protein families requires comparative analysis of their amino acid sequences through multiple sequence alignment. While a direct analysis of the resulting data allows to identify conserved regions, it does not provide a general and broad view on the proteins’ hierarchical organization and their distribution in the sequence, structural or functional spaces. Our project aims to develop a novel strategy for multiple sequence alignment visualization and interpretation using a powerful method demonstrated its efficiency for the hierarchy detection in multi-dimensional data sets called Poincaré maps.

DSIMB

Top repositories